Recognition modes of RNA tetraloops and tetraloop‐like motifs by RNA‐binding proteins
R Thapar, AP Denmon… - Wiley Interdisciplinary …, 2014 - Wiley Online Library
RNA hairpins are the most commonly occurring secondary structural elements in RNAs and
serve as nucleation sites for RNA folding, RNA–RNA, and RNA–protein interactions. RNA …
serve as nucleation sites for RNA folding, RNA–RNA, and RNA–protein interactions. RNA …
Structural basis for regulation of RNA-binding proteins by phosphorylation
R Thapar - ACS chemical biology, 2015 - ACS Publications
Ribonucleoprotein complexes involved in pre-mRNA splicing and mRNA decay are often
regulated by phosphorylation of RNA-binding proteins. Cells use phosphorylation …
regulated by phosphorylation of RNA-binding proteins. Cells use phosphorylation …
Replication-dependent histone biosynthesis is coupled to cell-cycle commitment
C Armstrong, SL Spencer - Proceedings of the National …, 2021 - National Acad Sciences
The current model of replication-dependent (RD) histone biosynthesis posits that RD histone
gene expression is coupled to DNA replication, occurring only in S phase of the cell cycle …
gene expression is coupled to DNA replication, occurring only in S phase of the cell cycle …
Mechanism of efficient double-strand break repair by a long non-coding RNA
Mechanistic studies in DNA repair have focused on roles of multi-protein DNA complexes,
so how long non-coding RNAs (lncRNAs) regulate DNA repair is less well understood. Yet …
so how long non-coding RNAs (lncRNAs) regulate DNA repair is less well understood. Yet …
Structure of histone mRNA stem-loop, human stem-loop binding protein, and 3′ hExo ternary complex
Metazoan replication-dependent histone messenger RNAs (mRNAs) have a conserved
stem-loop (SL) at their 3′-end. The stem-loop binding protein (SLBP) specifically …
stem-loop (SL) at their 3′-end. The stem-loop binding protein (SLBP) specifically …
[HTML][HTML] Roles of prolyl isomerases in RNA-mediated gene expression
R Thapar - Biomolecules, 2015 - mdpi.com
The peptidyl-prolyl cis-trans isomerases (PPIases) that include immunophilins (cyclophilins
and FKBPs) and parvulins (Pin1, Par14, Par17) participate in cell signaling, transcription …
and FKBPs) and parvulins (Pin1, Par14, Par17) participate in cell signaling, transcription …
Structured 3′ UTRs destabilize mRNAs in plants
Background RNA secondary structure (RSS) can influence the regulation of transcription,
RNA processing, and protein synthesis, among other processes. 3′ untranslated regions …
RNA processing, and protein synthesis, among other processes. 3′ untranslated regions …
Structure and function of pre-mRNA 5′-end capping quality control and 3′-end processing
Messenger RNA precursors (pre-mRNAs) are produced as the nascent transcripts of RNA
polymerase II (Pol II) in eukaryotes and must undergo extensive maturational processing …
polymerase II (Pol II) in eukaryotes and must undergo extensive maturational processing …
Regulation of AU-rich element RNA binding proteins by phosphorylation and the prolyl isomerase Pin1
ZJ Shen, JS Malter - Biomolecules, 2015 - mdpi.com
The accumulation of 3'untranslated region (3'-UTR), AU-rich element (ARE) containing
mRNAs, are predominantly controlled at the post-transcriptional level. Regulation appears to …
mRNAs, are predominantly controlled at the post-transcriptional level. Regulation appears to …
Molecular mechanisms for the regulation of histone mRNA stem-loop–binding protein by phosphorylation
Replication-dependent histone mRNAs end with a conserved stem loop that is recognized
by stem-loop–binding protein (SLBP). The minimal RNA-processing domain of SLBP is …
by stem-loop–binding protein (SLBP). The minimal RNA-processing domain of SLBP is …