Clinical tools and biomarkers to predict preeclampsia

TM MacDonald, SP Walker, NJ Hannan, S Tong… - …, 2022 - thelancet.com
Preeclampsia is pregnancy-specific, and significantly contributes to maternal, and perinatal
morbidity and mortality worldwide. An effective predictive test for preeclampsia would …

Potential biomarkers for late-onset and term preeclampsia: A scoping review

L Han, OJ Holland, F Da Silva Costa… - Frontiers in …, 2023 - frontiersin.org
Preeclampsia is a progressive, multisystem pregnancy disorder. According to the time of
onset or delivery, preeclampsia has been subclassified into early-onset (< 34 weeks) and …

[HTML][HTML] Perfluorobutane sulfonate exposure disrupted human placental cytotrophoblast cell proliferation and invasion involving in dysregulating preeclampsia related …

WP Marinello, ZS Mohseni… - … : official publication of …, 2020 - ncbi.nlm.nih.gov
We previously reported that maternal PFBS, an emerging pollutant, exposure is positively
associated with preeclampsia which can results from aberrant trophoblasts invasion and …

A disintegrin and metalloproteinase 12 (ADAM12) is reduced at 36 weeks' gestation in pregnancies destined to deliver small for gestational age infants

F Andres, GP Wong, SP Walker, TM MacDonald… - Placenta, 2022 - Elsevier
First trimester circulating ADAM12 is reduced in fetal growth restriction (FGR) and
preeclampsia. We measured plasma ADAM12 at 36 weeks' gestation preceding diagnosis …

MicroRNAs 363 and 149 are differentially expressed in the maternal circulation preceding a diagnosis of preeclampsia

CA Whigham, TM MacDonald, SP Walker, R Hiscock… - Scientific Reports, 2020 - nature.com
Preeclampsia is a pregnancy complication associated with angiogenic dysbalance,
maternal endothelial dysfunction and end-organ injury. A predictive test to identify those who …

Advances in preeclampsia testing

JJ Miller, V Higgins, A Ren, S Logan, PM Yip… - Advances in Clinical …, 2023 - Elsevier
Preeclampsia is a multisystem hypertensive disorder and one of the leading causes of
maternal and fetal morbidity and mortality. The clinical hallmarks such as hypertension and …

Evaluation of epigenetic age calculators between preeclampsia and normotensive pregnancies in an Australian cohort

P Pruszkowska-Przybylska, S Brennecke, EK Moses… - Scientific Reports, 2022 - nature.com
Advanced biological aging, as assessed through DNA methylation markers, is associated
with several complex diseases. The associations between maternal DNA methylation age …

Early mid-pregnancy blood-based proteins as possible biomarkers of increased infant birth size in sex-stratified analyses

E Lindberger, F Ahlsson, K Junus… - Reproductive …, 2023 - Springer
The objective of this study was to evaluate the associations of 92 maternal blood-based
proteins with increased infant birth size. The study was performed at the Uppsala University …

Higher serum adrenomedullin concentration is associated with an increased risk of gestational diabetes mellitus: A nested case-control study in Wuhan, China

X Yao, X Chen, REH Adam, Z Zhang, Y Ge, Y Li… - Nutrition Research, 2022 - Elsevier
Adrenomedullin (ADM) is thought to play a significant role in regulating insulin secretion and
glucose metabolism. However, studies on the relationship between ADM and gestational …

[HTML][HTML] 基于外周血游离RNA 分析预测孕妇子痫前期的研究进展

丽萍税, 文明许, 国琳何 - Journal of Sichuan University (Medical …, 2022 - ncbi.nlm.nih.gov
子痫前期严重影响母婴健康, 目前缺乏基于相关发病机制基础上的治疗方法,
亦无独立可靠的早期预测子痫前期的临床指标。 近期有研究表明通过对孕妇外周血游离RNA …