[HTML][HTML] IP-10 is highly involved in HIV infection

J Lei, X Yin, H Shang, Y Jiang - Cytokine, 2019 - Elsevier
Abstract Interferon-γ (IFN-γ)-induced protein 10 (IP-10 or CXCL-10) is a chemokine involved
in trafficking immune cells to inflammatory sites. Numerous studies have reported …

[HTML][HTML] HIV cure research: advances and prospects

CP Passaes, A Sáez-Cirión - Virology, 2014 - Elsevier
Thirty years after the identification of HIV, a cure for HIV infection is still to be achieved.
Advances of combined antiretroviral therapy (cART) in recent years have transformed HIV …

Adipose tissue is a neglected viral reservoir and an inflammatory site during chronic HIV and SIV infection

A Damouche, T Lazure, V Avettand-Fènoël… - PLoS …, 2015 - journals.plos.org
Two of the crucial aspects of human immunodeficiency virus (HIV) infection are (i) viral
persistence in reservoirs (precluding viral eradication) and (ii) chronic inflammation (directly …

Hospitalization rates and reasons among HIV elite controllers and persons with medically controlled HIV infection

TA Crowell, KA Gebo, JN Blankson… - The Journal of …, 2015 - academic.oup.com
Background. Elite controllers spontaneously suppress human immunodeficiency virus (HIV)
viremia but also demonstrate chronic inflammation that may increase risk of comorbid …

Plasma biomarkers for systemic inflammation in COVID‐19 survivors

J Zhao, M Schank, L Wang, X Dang… - PROTEOMICS …, 2022 - Wiley Online Library
Background While the majority of COVID‐19 patients fully recover from the infection and
become asymptomatic, a significant proportion of COVID‐19 survivors experience a broad …

Distinct inflammation-related proteins associated with T cell immune recovery during chronic HIV-1 infection

LY Wan, HH Huang, C Zhen, SY Chen… - Emerging Microbes & …, 2023 - Taylor & Francis
Chronic inflammation and T cell dysregulation persist in individuals infected with human
immunodeficiency virus type 1 (HIV-1), even after successful antiretroviral treatment. The …

HIV control: Is getting there the same as staying there?

P Goulder, SG Deeks - PLoS pathogens, 2018 - journals.plos.org
In this brief review and perspective, we address the question of whether the immune
responses that bring about immune control of acute HIV infection are the same as, or distinct …

HIV-1 Vpu is a potent transcriptional suppressor of NF-κB-elicited antiviral immune responses

S Langer, C Hammer, K Hopfensperger, L Klein… - Elife, 2019 - elifesciences.org
Many viral pathogens target innate sensing cascades and/or cellular transcription factors to
suppress antiviral immune responses. Here, we show that the accessory viral protein U …

Factors leading to the loss of natural elite control of HIV-1 infection

M Pernas, L Tarancon-Diez… - Journal of …, 2018 - Am Soc Microbiol
ABSTRACT HIV-1 elite controllers (EC) maintain undetectable viral loads (VL) in the
absence of antiretroviral treatment. However, these subjects have heterogeneous clinical …

Cellular and molecular insights into incomplete immune recovery in HIV/AIDS patients

L Yan, K Xu, Q Xiao, L Tuo, T Luo, S Wang… - Frontiers in …, 2023 - frontiersin.org
Highly active antiretroviral therapy (ART) can effectively inhibit virus replication and restore
immune function in most people living with human immunodeficiency virus (HIV). However …