[HTML][HTML] Insights into therapy resistance in cervical cancer

IA George, R Chauhan, RE Dhawale, R Iyer… - Advances in Cancer …, 2022 - Elsevier
Abstract Treatment failure is one of the main hurdles in treating cervical cancer, despite
significant breakthroughs in both conventional and targeted therapy. The one-year survival …

Epithelial-mesenchymal transition process during embryo implantation

F Oghbaei, R Zarezadeh, D Jafari-Gharabaghlou… - Cell and tissue …, 2022 - Springer
The epithelial to mesenchymal transition (EMT) in endometrial epithelial and trophectoderm
cells is essential for the progression of embryo implantation and its impairment could cause …

[HTML][HTML] Chloride channelopathies

R Planells-Cases, TJ Jentsch - … et Biophysica Acta (BBA)-Molecular Basis …, 2009 - Elsevier
Channelopathies, defined as diseases that are caused by mutations in genes encoding ion
channels, are associated with a wide variety of symptoms. Impaired chloride transport can …

Construction and analysis of the tumor-specific mRNA–miRNA–lncRNA network in gastric cancer

X Zheng, X Wang, L Zheng, H Zhao, W Li… - Frontiers in …, 2020 - frontiersin.org
Weighted correlation network analysis (WGCNA) is a statistical method that has been widely
used in recent years to explore gene co-expression modules. Competing endogenous RNA …

Solute carriers (SLCs) in cancer

S El-Gebali, S Bentz, MA Hediger, P Anderle - Molecular aspects of …, 2013 - Elsevier
During tumor progression cells acquire an altered metabolism, either as a cause or as a
consequence of an increased need of energy and nutrients. All four major classes of …

Loss of CLCA4 promotes epithelial-to-mesenchymal transition in breast cancer cells

Y Yu, V Walia, RC Elble - PloS one, 2013 - journals.plos.org
The epithelial to mesenchymal transition (EMT) is a developmental program in which
epithelial cells downregulate their cell-cell junctions, acquire spindle cell morphology and …

[HTML][HTML] Integrated K+ channel and K+ Cl-cotransporter functions are required for the coordination of size and proportion during development

JS Lanni, D Peal, L Ekstrom, H Chen, C Stanclift… - Developmental …, 2019 - Elsevier
The coordination of growth during development establishes proportionality within and
among the different anatomic structures of organisms. Innate memory of this proportionality …

Cross‐talk between zinc and calcium regulates ion transport: A role for the zinc receptor, ZnR/GPR39

M Hershfinkel - The Journal of Physiology, 2024 - Wiley Online Library
Zinc is essential for many physiological functions, with a major role in digestive system, skin
health, and learning and memory. On the cellular level, zinc is involved in cell proliferation …

The biogenesis of potassium transporters: implications of disease-associated mutations

M Kok, JL Brodsky - Critical Reviews in Biochemistry and Molecular …, 2024 - Taylor & Francis
The concentration of intracellular and extracellular potassium is tightly regulated due to the
action of various ion transporters, channels, and pumps, which reside primarily in the kidney …

Axonal and periaxonal swelling precede peripheral neurodegeneration in KCC3 knockout mice

N Byun, E Delpire - Neurobiology of disease, 2007 - Elsevier
We have previously reported CNS and locomotor deficits in KCC3 knockout mice, an animal
model of agenesis of the corpus callosum associated with peripheral neuropathy …