The role of the gut microbiome in colorectal cancer development and therapy response

L Sánchez-Alcoholado, B Ramos-Molina, A Otero… - Cancers, 2020 - mdpi.com
Colorectal cancer (CRC) is the third most common cancer worldwide and the leading cause
of cancer-related deaths. Recently, several studies have demonstrated that gut microbiota …

Flavonoids and cancer prevention: a review of the evidence

DF Romagnolo, OI Selmin - Journal of nutrition in gerontology and …, 2012 - Taylor & Francis
The objective of this work is to review data from epidemiological and preclinical studies
addressing the potential benefits of diets based on flavonoids for cancer prevention …

Cancer chemoprevention through dietary flavonoids: what's limiting?

H Amawi, CR Ashby, AK Tiwari - Chinese journal of cancer, 2017 - Springer
Flavonoids are polyphenols that are found in numerous edible plant species. Data obtained
from preclinical and clinical studies suggest that specific flavonoids are chemo-preventive …

Dietary phytochemicals in colorectal cancer prevention and treatment: A focus on the molecular mechanisms involved

S Afrin, F Giampieri, M Gasparrini… - Biotechnology …, 2020 - Elsevier
Worldwide, colorectal cancer (CRC) remains a major cancer type and leading cause of
death. Unfortunately, current medical treatments are not sufficient due to lack of effective …

The relationship between the structure and biological actions of green tea catechins

C Braicu, MR Ladomery, VS Chedea, A Irimie… - Food chemistry, 2013 - Elsevier
Catechins and their gallate esters are a class of polyphenolic compounds. The catechin
subclass known as flavan-3-ols have recently attracted much attention with regards to their …

Isolation of catechin‐converting human intestinal bacteria

M Kutschera, W Engst, M Blaut… - Journal of Applied …, 2011 - academic.oup.com
Aims: To isolate and characterize bacteria from the human intestine that are involved in the
conversion of catechins, a class of bioactive polyphenols abundant in the human diet …

Dietary flavonoids and the risk of colorectal cancer: An updated meta-analysis of epidemiological studies

H Chang, L Lei, Y Zhou, F Ye, G Zhao - Nutrients, 2018 - mdpi.com
Aim: The aim of this study was to perform an up-to-date meta-analysis of the association
between the intake of dietary flavonoids and the risk of colorectal cancer. Methods: The …

Kaempferol induced apoptosis via endoplasmic reticulum stress and mitochondria‐dependent pathway in human osteosarcoma U‐2 OS cells

WW Huang, YJ Chiu, MJ Fan, HF Lu… - Molecular nutrition & …, 2010 - Wiley Online Library
Kaempferol is a natural flavonoid. Previous studies have reported that kaempferol has anti‐
proliferation activities and induces apoptosis in many cancer cell lines. However, there are …

Phytochemicals and cancer risk: a review of the epidemiological evidence

PE Miller, DC Snyder - Nutrition in Clinical Practice, 2012 - Wiley Online Library
A number of epidemiological studies have investigated associations between various
phytochemicals and cancer risk. Phytoestrogens and carotenoids are the two most …

Polyphenol supplementation as a complementary medicinal approach to treating inflammatory bowel disease

F Biasi, M Astegiano, M Maina… - Current medicinal …, 2011 - ingentaconnect.com
Inflammatory bowel disease (IBD) comprises a group of idiopathic chronic intestinal
inflammation syndromes that are very common in developed countries. It is characterized by …