Any account of “what is special about the human brain”(Passingham 2008) must specify the
neural basis of our unique ability to produce speech and delineate how these remarkable …

Purpose Identifying risk factors associated with neurodevelopmental disorders is an
important line of research, as it will lead to earlier identification of children who could benefit …

Congenital amusia (commonly known as tone deafness) is a lifelong musical disorder that
affects 4% of the population according to a single estimate based on a single test from 1980 …

The past decade of research has provided compelling evidence that musical engagement is
a fundamental human trait, and its biological basis is increasingly scrutinized. In this …

Development of proficient spoken language skills is disrupted by mutations of the FOXP2
transcription factor. A heterozygous missense mutation in the KE family causes speech …

Advances in molecular technologies make it possible to pinpoint genomic factors associated
with complex human traits. For cognition and behaviour, identification of underlying genes …

Next-generation sequencing recently revealed that recurrent disruptive mutations in a few
genes may account for 1% of sporadic autism cases. Coupling these novel genetic data to …

Investigation of the biological basis of human speech and language is being transformed by
developments in molecular technologies, including high-throughput genotyping and next …

Abstract Individuals with heterozygous 16p11. 2 deletions reportedly suffer from a variety of
difficulties with speech and language. Indeed, recent copy-number variant screens of …

Background Childhood apraxia of speech (CAS) is a rare, severe, persistent pediatric motor
speech disorder with associated deficits in sensorimotor, cognitive, language, learning and …