Fluoride is often added to drinking water and toothpaste because of its beneficial effects in
dental health. It is also administered in the treatment of osteoporosis. 1 While the beneficial …

The field of 18F chemistry is rapidly expanding because of the use of this radionuclide in
radiotracers for positron emission tomography (PET). Until recently, most [18F]-radiotracers …

The coordination chemistry of a new pentadentate bifunctional chelator (BFC), NODA-MPAA
1, containing the 1, 4, 7-triazacyclononane-1, 4-diacetate (NODA) motif with a …

Facile based promoted deboronation of electron-deficient arylboronate esters was observed
for arylboronates containing two ortho electron-withdrawing group (EWG) substituents …

Positron emission tomography (PET) is a powerful technique for imaging biological
pathways in vivo, particularly those that are key targets in disease processes. In contrast …

Unorthodox 18F-labeling strategies not employing the formation of a carbon-18F bond are
seldom found in radiochemistry. Historically, the formation of a boron-or silicon-18F bond …

Whereas electron withdrawing substituents retard the rate of aryltrifluoroborate solvolysis,
electron-donating groups enhance it. Herein is presented a Hammett analysis of the …

Conventional methods for radiolabelling biomolecules such as proteins and peptides with
fluorine-18 for PET imaging rely on carbon–fluorine bond formation and are complex and …

The use of a boronic ester as a captor of aqueous [18F]-fluoride has been previously
suggested as a means of labeling biomolecules in one step for positron emission …

We combine a novel boronate trap for F− with a near-infrared fluorophore into a single
molecule. Attachment to targeting ligands enables localization by positron emission …