[HTML][HTML] Progress and remaining challenges in high-throughput volume electron microscopy

J Kornfeld, W Denk - Current opinion in neurobiology, 2018 - Elsevier
Highlights•Breakthrough in automatic neuron reconstruction from VEM data will enable the
reconstruction of much larger data sets in the future.•Volume electron microscopy imaging …

Adaptive template transformer for mitochondria segmentation in electron microscopy images

Y Pan, N Luo, R Sun, M Meng… - Proceedings of the …, 2023 - openaccess.thecvf.com
Mitochondria, as tiny structures within the cell, are of significant importance to study cell
functions for biological and clinical analysis. And exploring how to automatically segment …

Learning from connectomics on the fly

P Schlegel, M Costa, GSXE Jefferis - Current opinion in insect science, 2017 - Elsevier
Highlights•Whole brain EM connectomics will revolutionise neuroscience.•Insects are at the
forefront of this revolution.•Mapping between light and EM image data can integrate …

[HTML][HTML] EM connectomics reveals axonal target variation in a sequence-generating network

J Kornfeld, SE Benezra, RT Narayanan, F Svara… - Elife, 2017 - elifesciences.org
The sequential activation of neurons has been observed in various areas of the brain, but in
no case is the underlying network structure well understood. Here we examined the circuit …

Fast mitochondria detection for connectomics

V Casser, K Kang, H Pfister… - Medical Imaging with …, 2020 - proceedings.mlr.press
High-resolution connectomics data allows for the identification of dysfunctional mitochondria
which are linked to a variety of diseases such as autism or bipolar. However, manual …

[HTML][HTML] Scalable interactive visualization for connectomics

D Haehn, J Hoffer, B Matejek, A Suissa-Peleg… - Informatics, 2017 - mdpi.com
Connectomics has recently begun to image brain tissue at nanometer resolution, which
produces petabytes of data. This data must be aligned, labeled, proofread, and formed into …

The mixture graph-a data structure for compressing, rendering, and querying segmentation histograms

K Al-Thelaya, M Agus… - IEEE Transactions on …, 2020 - ieeexplore.ieee.org
In this paper, we present a novel data structure, called the Mixture Graph. This data structure
allows us to compress, render, and query segmentation histograms. Such histograms arise …

[PDF][PDF] Fast mitochondria segmentation for connectomics

V Casser, K Kang, H Pfister… - arXiv preprint arXiv …, 2018 - researchgate.net
In connectomics, scientists create the wiring diagram of a mammalian brain by identifying
synaptic connections between neurons in nano-scale electron microscopy images. This …

[HTML][HTML] Large-scale neuroanatomy using LASSO: loop-based automated serial sectioning operation

TJ Lee, A Kumar, AH Balwani, D Brittain, S Kinn… - PLoS …, 2018 - journals.plos.org
Serial section transmission electron microscopy (ssTEM) is the most promising tool for
investigating the three-dimensional anatomy of the brain with nanometer resolution. Yet as …

VICE: Visual identification and correction of neural circuit errors

F Gonda, X Wang, J Beyer, M Hadwiger… - Computer graphics …, 2021 - Wiley Online Library
A connectivity graph of neurons at the resolution of single synapses provides scientists with
a tool for understanding the nervous system in health and disease. Recent advances in …