Pancreatic cancer is an aggressive malignancy with increasing incidence and poor
prognosis due to its late diagnosis and intrinsic chemoresistance. Most pancreatic cancer …

As a kinase at the crossroads of numerous metabolic and cell growth signaling pathways,
glycogen synthase kinase-3 beta (GSK-3β) is a highly desirable therapeutic target in cancer …

Visceral adipose tissue plays a critical role in numerous diseases. Although imaging studies
often show adipose involvement in abdominal diseases, their outcomes may vary from being …

Based on high quality surgery and scientific data, scientists and surgeons are committed to
protecting patients as well as healthcare staff and hereby provide this Guidance to address …

Pancreatic cancer (PC) is the deadliest neoplastic epithelial malignancies and is projected
to be the second leading cause of cancer-related mortality by 2024. Five years overall …

Acinar-to-ductal metaplasia (ADM) is a recently recognized, yet less well-studied, precursor
lesion of pancreatic ductal adenocarcinoma (PDAC) developed in the setting of chronic …

Purpose: Pancreatic ductal adenocarcinoma (PDAC) is a predominantly fatal common
malignancy with inadequate treatment options. Glycogen synthase kinase 3β (GSK-3β) is an …

Pancreatic ductal metaplasia (PDM) is the transformation of potentially many type of cells in
pancreas into ductal or ductal-like cells, which eventually replace the existing differentiated …

Introduction: Pancreatic ductal adenocarcinoma (PDAC) is the third leading cause of cancer
death in the United States with a single-digit 5-year survival rate despite advances in …

Glycogen synthase kinase-3 beta (GSK-3β), a serine/threonine kinase, has been identified
as a potential therapeutic target in human bladder cancer. In the present study, we …