Chronic kidney disease in aged cats: clinical features, morphology, and proposed pathogeneses

CA Brown, J Elliott, CW Schmiedt… - Veterinary …, 2016 - journals.sagepub.com
Chronic kidney disease (CKD) is the most common metabolic disease of domesticated cats,
with most affected cats being geriatric (> 12 years of age). The prevalence of CKD in cats …

Renal biomarkers in cats: A review of the current status in chronic kidney disease

T Kongtasai - JOURNAL OF JAPANESE ASSOCIATION OF …, 2024 - jstage.jst.go.jp
Serum creatinine concentration, the classical biomarker of chronic kidney disease (CKD) in
cats, has important limitations that decrease its value as a biomarker of early CKD. Recently …

[HTML][HTML] Roles of mesenchymal stem cells in tissue regeneration and immunomodulation

AP Ayala-Cuellar, JH Kang, EB Jeung… - Biomolecules & …, 2019 - ncbi.nlm.nih.gov
Mesenchymal stem cells are classified as multipotent stem cells, due to their capability to
transdifferentiate into various lineages that develop from mesoderm. Their popular appeal …

Red meat intake in chronic kidney disease patients: Two sides of the coin

D Mafra, NA Borges, LFM de Franca Cardozo, JS Anjos… - Nutrition, 2018 - Elsevier
Red meat is an important dietary source of high biological value protein and micronutrients
such as vitamins, iron, and zinc that exert many beneficial functions. However, high …

Mineral analysis of complete dog and cat foods in the UK and compliance with European guidelines

M Davies, R Alborough, L Jones, C Davis… - Scientific Reports, 2017 - nature.com
Mineral content of complete pet food is regulated to ensure health of the companion animal
population. Analysis of adherence to these regulatory guidelines has not been conducted …

Naringin attenuates renal interstitial fibrosis by regulating the TGF‑β/Smad signaling pathway and inflammation

R Wang, G Wu, T Dai, Y Lang… - Experimental and …, 2021 - spandidos-publications.com
Interstitial fibrosis is a typical feature of all progressive renal diseases. The process of
fibrosis is frequently coupled with the presence of pro‑fibrotic factors and inflammation …

Bone marrow mesenchymal stem cell-derived extracellular vesicles containing miR-181d protect rats against renal fibrosis by inhibiting KLF6 and the NF-κB signaling …

SJ Wang, ZZ Qiu, FW Chen, AL Mao, JC Bai… - Cell Death & …, 2022 - nature.com
Recent studies have investigated the ability of extracellular vesicles (EVs) in regulating
neighboring cells by transferring signaling molecules, such as microRNAs (miRs) in renal …

Clinical progression of cats with early‐stage chronic kidney disease fed diets with varying protein and phosphorus contents and calcium to phosphorus ratios

S Schauf, JC Coltherd, J Atwal… - Journal of Veterinary …, 2021 - Wiley Online Library
Background Dietary protein and phosphorus (P) restriction is the mainstay for nutritional
management of chronic kidney disease (CKD). However, adequate restriction levels for cats …

Salvianolic acid A attenuates kidney injury and inflammation by inhibiting NF-κB and p38 MAPK signaling pathways in 5/6 nephrectomized rats

H Zhang, Y Wang, C Gao, Y Gu, J Huang… - Acta Pharmacologica …, 2018 - nature.com
Salvianolic acid A (SAA) is a minor phenolic carboxylic acid extracted from Salviae
miltiorrhizae Bunge (Danshen). SAA exhibits a variety of pharmacological activities, such as …

Extracellular matrix roles in cardiorenal fibrosis: Potential therapeutic targets for CVD and CKD in the elderly

H Toba, ML Lindsey - Pharmacology & therapeutics, 2019 - Elsevier
Whereas hypertension, diabetes, and dyslipidemia are age-related risk factors for
cardiovascular disease (CVD) and chronic kidney disease (CKD), aging alone is an …