Nonenzymatic reactions in natural product formation

LM Bouthillette, V Aniebok, DA Colosimo… - Chemical …, 2022 - ACS Publications
Biosynthetic mechanisms of natural products primarily depend on systems of protein
catalysts. However, within the field of biosynthesis, there are cases in which the inherent …

Naturally Occurring Organohalogen Compounds—A Comprehensive Review

GW Gribble - Naturally Occurring Organohalogen Compounds, 2023 - Springer
The present volume is the third in a trilogy that documents naturally occurring
organohalogen compounds, bringing the total number—from fewer than 25 in 1968—to …

Chimeric natural products derived from medermycin and the nature-inspired construction of their polycyclic skeletons

S Yin, Z Liu, J Shen, Y Xia, W Wang, P Gui… - Nature …, 2022 - nature.com
Medermycin, produced by Streptomyces species, represents a family of antibiotics with
significant activity against Gram-positive pathogens. The biosynthesis of this family of natural …

Pyochelin Biosynthetic Metabolites Bind Iron and Promote Growth in Pseudomonads Demonstrating Siderophore-like Activity

AR Kaplan, DG Musaev, WM Wuest - ACS infectious diseases, 2021 - ACS Publications
Pseudomonads employ several strategies to sequester iron vital for their survival including
the use of siderophores such as pyoverdine and pyochelin. Similar in structure but …

[图书][B] Naturally occurring organohalogen compounds

GW Gribble - 2023 - Springer
The previous two surveys documented a combined total of 4714 naturally occurring
organohalogen compounds, both biogenic and abiotic [1, 2]. In the subsequent two …

Mo–Catalyzed One‐Pot Synthesis of N‐Polyheterocycles from Nitroarenes and Glycols with Recycling of the Waste Reduction Byproduct. Substituent‐Tuned …

R Hernández‐Ruiz, R Rubio‐Presa… - … A European Journal, 2021 - Wiley Online Library
A catalytic domino reduction–imine formation–intramolecular cyclization–oxidation for the
general synthesis of a wide variety of biologically relevant N‐polyheterocycles, such as …

Boron NMR as a method to screen natural product libraries for B-containing compounds

JM Macho, RM Blue, HW Lee, JB MacMillan - Organic Letters, 2022 - ACS Publications
Natural products are biologically relevant metabolites exploited for biomedicine and
biotechnology. The frequent reisolation of known natural products questions whether …

Biomimetic Total Synthesis and Investigation of the Non‐Enzymatic Chemistry of Oxazinin A

V Aniebok, RD Shingare, H Wei‐Lee… - Angewandte Chemie …, 2022 - Wiley Online Library
We report the first total synthesis of an antimycobacterial natural product oxazinin A that
takes advantage of a multi‐component cascade reaction of anthranilic acid and a precursor …

Structurally Diverse Macrolactams from an Antarctic Streptomyces Species

J Shen, J Sun, S Yin, W Zhu, P Fu - Journal of Natural Products, 2024 - ACS Publications
Twelve new polyenic macrolactams, cyclamenols G–R (1 and 3–13), together with the
known analogue cyclamenol A (2), were isolated from Streptomyces sp. OUCMDZ-4348 …

DABSO-mediated Pummerer reaction enables one-pot synthesis of pyrroloquinolines for accessing marinoquinolines: mechanistic, photophysical and …

R Khan, DK Penthi, A Chatterjee, C Sahoo… - Organic Chemistry …, 2025 - pubs.rsc.org
A new one-pot acid-and exogenous oxidant-free synthesis of pyrrolo [2, 3-c] quinolines has
been developed. This strategy involves the chemoselective reduction of 3-(2-nitrophenyl) …