Glutamine‐derived peptides: Current progress and future directions

T Yu, T Hu, K Na, L Zhang, S Lu… - … Reviews in Food …, 2024 - Wiley Online Library
Glutamine, the most abundant amino acid in the body, plays a critical role in preserving
immune function, nitrogen balance, intestinal integrity, and resistance to infection. However …

Alanyl-Glutamine Dipeptide attenuates non-alcoholic fatty liver Disease Induced by a high-Fat Diet in mice by improving gut microbiota dysbiosis

Y Zheng, H Ying, J Shi, L Li, Y Zhao - Nutrients, 2023 - mdpi.com
Non-alcoholic fatty liver disease (NAFLD) manifests as a persistent liver ailment marked by
the excessive buildup of lipids within the hepatic organ accompanied by inflammatory …

A mixed antioxidant supplement improves cognitive function, and coordination in aged mice

K Fukui, F You, Y Kato, S Yuzawa… - Journal of Clinical …, 2023 - pmc.ncbi.nlm.nih.gov
Accumulation of oxidative damage increases the risk of several disorders. To prevent these
diseases, people consume supplements. However, there is little evidence of the impact of …

Multiplex gene knockout raises Ala-Gln production by Escherichia coli expressing amino acid ester acyltransferase

Z Jing, J Xu, J Liu, C Du, J Qi, C Fan, Y Li… - Applied Microbiology and …, 2023 - Springer
Abstract L-Alanyl-L-Glutamine (Ala-Gln) is a common parenteral nutritional supplement. In
our previous study, the recombinant whole-cell catalyst Escherichia coli BL21 (DE3) …

[HTML][HTML] Alanyl-Glutamine Protects Mice against Methionine-and Choline-Deficient-Diet-Induced Steatohepatitis and Fibrosis by Modulating Oxidative Stress and …

J Hu, Y Zheng, H Ying, H Ma, L Li, Y Zhao - Nutrients, 2022 - mdpi.com
Nonalcoholic steatohepatitis (NASH) is a common chronic liver disease with increasing
prevalence rates over years and is associated with hepatic lipid accumulation, liver injury …

Integrated Analysis of Gut Microbiome and Liver Metabolome to Evaluate the Effects of Fecal Microbiota Transplantation on Lipopolysaccharide/D-galactosamine …

C Yuan, J Fan, L Jiang, W Ye, Z Chen, W Wu, Q Huang… - Nutrients, 2023 - mdpi.com
Acute liver failure (ALF) refers to the occurrence of massive hepatocyte necrosis in a short
time, with multiple complications, including inflammatory response, hepatic encephalopathy …

Influence of the glutamate-glutamine cycle on valproic acid-associated hepatotoxicity in pediatric patients with epilepsy

L Ma, J Zhu, X Kong, L Chen, J Du, L Yang… - Clinical …, 2024 - Taylor & Francis
Introduction Although valproic acid is generally well tolerated, hepatotoxicity is a common
side effect in patients receiving long-term treatment. However, the mechanisms underlying …

[HTML][HTML] IDH1/MDH1 deacetylation promotes NETosis by regulating OPA1 and autophagy

Y Wang, J Guo, D Zhang, C Shi, X Zhang… - International …, 2024 - Elsevier
Background As a heterogeneous and life-threatening disease, the pathogenesis of acute
liver failure (ALF) is complex. Our previous study has shown that IDH1/MDH1 deacetylation …

Multi-omics and chemical profiling approaches to understand the material foundation and pharmacological mechanism of sophorae tonkinensis radix et rhizome …

SW Rao, CJ Liu, D Liang, YY Duan, ZH Chen… - Journal of …, 2024 - Elsevier
Abstract Ethnopharmacological relevance Sophorae tonkinensis Radix et Rhizoma (STR) is
an extensively applied traditional Chinese medicine (TCM) in southwest China. However, its …

[HTML][HTML] Effects of Alanyl-Glutamine Dipeptide Supplementation on Growth Performance, Nutrient Digestibility, Digestive Enzyme Activity, Immunity, and Antioxidant …

U Nazir, Z Fu, X Zheng, MH Zafar, Y Chen, Z Yang… - Animals, 2024 - mdpi.com
Simple Summary Alanyl-glutamine dipeptide carries utmost importance for the poultry
industry due to its potential for enhancing various aspects of health and performance in …