Thiram exposure in environment: A critical review on cytotoxicity

K Liu, Y Li, M Iqbal, Z Tang, H Zhang - Chemosphere, 2022 - Elsevier
Thiram is used in large quantities in agriculture and may contaminate the environment by
improper handling or storage in chemical plants and warehouses. A review of the literature …

Chemically induced models of Parkinson's disease: history and perspectives for the involvement of ferroptosis

S Wen, T Aki, K Unuma, K Uemura - Frontiers in cellular …, 2020 - frontiersin.org
Ferroptosis is a newly discovered form of necrotic cell death characterized by its
dependency on iron and lipid peroxidation. Ferroptosis has attracted much attention recently …

[HTML][HTML] Exposure to dithiocarbamate fungicide maneb in vitro and in vivo: Neuronal apoptosis and underlying mechanisms

C Liu, Z Liu, Y Fang, Z Liao, Z Zhang, X Yuan… - Environment …, 2023 - Elsevier
Maneb, a widely-used dithiocarbamate fungicide, remains in the environment and exerts
adverse health effects. Epidemiological evidence shows that maneb exposure is associated …

Exposure to the environmentally toxic pesticide maneb induces Parkinson's disease-like neurotoxicity in mice: A combined proteomic and metabolomic analysis

C Liu, Z Liu, Y Fang, Z Du, Z Yan, X Yuan, L Dai, T Yu… - Chemosphere, 2022 - Elsevier
Maneb is a typical dithiocarbamate fungicide that has been extensively used worldwide.
Epidemiological evidence shows that exposure to maneb is an environmental risk factor for …

Thiram-induced cytotoxicity and oxidative stress in human erythrocytes: an in vitro study

S Salam, A Arif, R Mahmood - Pesticide biochemistry and physiology, 2020 - Elsevier
Tetramethylthiuram disulfide, commonly known as thiram, is an organosulfur compound
which is used as a bactericide, fungicide and ectoparasiticide to prevent disease in seeds …

Maneb alters central carbon metabolism and thiol redox status in a toxicant model of Parkinson's disease

CC Anderson, JO Marentette, AK Rauniyar… - Free Radical Biology …, 2021 - Elsevier
The dithiocarbamate fungicide maneb (MB) has attracted interest due to increasing concern
of the negative health effects of pesticides, as well as its association with Parkinson's …

Developmental neurotoxicity of maneb: Notochord defects, mitochondrial dysfunction and hypoactivity in zebrafish (Danio rerio) embryos and larvae

F Cao, CL Souders II, P Li, S Pang, X Liang… - Ecotoxicology and …, 2019 - Elsevier
Broad applications and exposure to the fungicide maneb can lead to toxicity in non-target
organisms. Maneb is also associated with neurogenerative diseases such as Parkinson's …

Toxic effects of a mancozeb-containing commercial formulation at environmental relevant concentrations on zebrafish embryonic development

R Vieira, CAS Venâncio, LM Félix - Environmental Science and Pollution …, 2020 - Springer
The toxicological knowledge of mancozeb (MZ)-containing commercial formulations on non-
target species is scarce and limited. Therefore, the objective of this work was to represent a …

Low concentrations of ethylene bisdithiocarbamate pesticides maneb and mancozeb impair manganese and zinc homeostasis to induce oxidative stress and caspase …

K Petitjean, Y Verres, S Bristeau, C Ribault, C Aninat… - Chemosphere, 2024 - Elsevier
The worldwide and intensive use of phytosanitary compounds results in environmental and
food contamination by chemical residues. Human exposure to multiple pesticide residues is …

Neurotoxicity assessment of QoI strobilurin fungicides azoxystrobin and trifloxystrobin in human SH-SY5Y neuroblastoma cells: Insights from lipidomics and …

K Nguyen, CL Sanchez, E Brammer-Robbins… - Neurotoxicology, 2022 - Elsevier
Strobilurin fungicides are quinone outside inhibitors (QoI) used to treat fungal pathogens for
agricultural and residential use. Here, we compared the potential for neurotoxicity of the …