The parasite, Toxoplasma gondii, is a highly successful pathogen that infects around 30% of
the global human population. Additionally, it is able to infect all warm blooded animals with …

Protozoan parasites cause severe morbidity and mortality in humans worldwide, especially
in developing countries where access to chemotherapeutic agents is limited. Although …

Protozoan infections are a serious global health problem,. Natural killer (NK) cells and
cytolytic T lymphocytes (CTLs) eliminate pathogen-infected cells by releasing cytolytic …

To determine changes in incidence of reactivation of Toxoplasma gondii infection,
manifesting as toxoplasmic encephalitis, and to assess the immunological mechanisms …

The intracellular parasite Toxoplasma gondii infects a wide variety of vertebrate species
globally. Infection in most hosts causes a lifelong chronic infection and generates …

We reported earlier that during chronic toxoplasmosis CD8+ T cells become functionally
exhausted with concomitant PD-1 upregulation, leading to eventual host mortality. However …

Glycosylphosphatidylinositols (GPIs) are highly conserved anchors for eukaryotic cell
surface proteins. The apicomplexan parasite, Toxoplasma gondii, is a widespread …

Toxoplasma gondii is the protozoan causative agent of toxoplasmosis in humans and warm-
blooded animals. Recent studies have illustrated that the immune system plays a pivotal role …

The tight relationship between immunity and retinoid levels provides evidence on the critical
role of retinoic acid (RA) in regulating immune activity, especially the mucosal one. Mucosal …

Toxoplasma gondii infection in mice provides an excellent model for the study of CD8+ T cell
responses. Natural and engineered T. gondii antigens have led the way to understanding …