Several editions of the World Health Organization (WHO) classifications of lympho‐
hemopoietic neoplasms in 2001, 2008, and 2016 served as the international standard for …

Clonal hematopoiesis (CH) is an age-related process whereby hematopoietic stem and
progenitor cells (HSPCs) acquire mutations that lead to a proliferative advantage and clonal …

Somatic mutations in UBA1 cause vacuoles, E1 ubiquitin-activating enzyme, X-linked,
autoinflammatory somatic (VEXAS) syndrome, an adult-onset inflammatory disease with an …

Over the past few years, we have gained a deeper understanding of clonal hematopoiesis of
indeterminate potential (CHIP), especially with regard to the epidemiology, clinical …

Clonal hematopoiesis (CH) is the development of a certain cell lineage which is the
cornerstone of hematologic malignancy especially myeloid neoplasms, however, can also …

PURPOSE Thrombocytopenia is a relatively common dose-limiting toxicity during peptide
receptor radionuclide therapy (PRRT) in patients with NET. Although uncommon, some …

Therapy-related myeloid neoplasms (t-MN) are aggressive leukemia that develops as a
complication of prior exposure to DNA-damaging agents. Clonal cytopenia of undetermined …

Clonal cytopenia of undetermined significance (CCUS) is defined by a myeloid driver
mutation in the context of otherwise unexplained cytopenia. CCUS has an inherent risk of …

Myeloid neoplasms include myeloproliferative and myelodysplastic neoplasms and acute
myeloid leukaemia. Historically, these diseases have been diagnosed based on …

The age‐associated mutational state of clonal haematopoiesis (CH) is linked to multiple
adverse health outcomes. As higher risk CH can lead to progressive neoplastic or vascular …