Shared and divergent neurocognitive impairments in adult patients with schizophrenia and bipolar disorder: Whither the evidence?
Recent data from genetic and brain imaging studies have urged rethinking of bipolar
disorder (BD) and schizophrenia (SCZ) as lying along a continuum of major endogenous …
disorder (BD) and schizophrenia (SCZ) as lying along a continuum of major endogenous …
Advancing biomarker research: utilizing 'Big Data'approaches for the characterization and prevention of bipolar disorder
RS McIntyre, DS Cha, JM Jerrell… - Bipolar …, 2014 - Wiley Online Library
Objective To provide a strategic framework for the prevention of bipolar disorder (BD) that
incorporates a 'Big Data'approach to risk assessment for BD. Methods Computerized …
incorporates a 'Big Data'approach to risk assessment for BD. Methods Computerized …
SorCS2 is required for BDNF-dependent plasticity in the hippocampus
S Glerup, U Bolcho, S Mølgaard, S Bøggild… - Molecular …, 2016 - nature.com
SorCS2 is a member of the Vps10p-domain receptor gene family receptors with critical roles
in the control of neuronal viability and function. Several genetic studies have suggested …
in the control of neuronal viability and function. Several genetic studies have suggested …
Does cognitive dysfunction in bipolar disorder qualify as a diagnostic intermediate phenotype?—a perspective paper
LV Kessing, K Miskowiak - Frontiers in psychiatry, 2018 - frontiersin.org
The present perspective paper addresses and discusses whether cognitive dysfunction in
bipolar disorder qualifies as a diagnostic intermediate phenotype using the Robin and Guze …
bipolar disorder qualifies as a diagnostic intermediate phenotype using the Robin and Guze …
The impact of childhood trauma on cognitive functioning in patients recently recovered from a first manic episode: data from the Systematic Treatment Optimization …
Background: Both bipolar disorder (BD) and childhood trauma are associated with cognitive
impairment. People with BD have high rates of childhood trauma, which confer greater …
impairment. People with BD have high rates of childhood trauma, which confer greater …
Association study of neuregulin-1 gene polymorphisms in a North Indian schizophrenia sample
BACKGROUND: Neuregulin-1 (NRG1) gene polymorphisms have been proposed as risk
factors for several common disorders. Associations with cognitive variation have also been …
factors for several common disorders. Associations with cognitive variation have also been …
The relationship between genetic risk variants with brain structure and function in bipolar disorder: a systematic review of genetic-neuroimaging studies
Genetic-neuroimaging paradigms could provide insights regarding the pathophysiology of
bipolar disorder (BD). Nevertheless, findings have been inconsistent across studies. A …
bipolar disorder (BD). Nevertheless, findings have been inconsistent across studies. A …
[HTML][HTML] Attention impairment in bipolar disorder: A systematic review.
EVM Camelo, B Velasques, P Ribeiro… - Psychology & …, 2013 - psycnet.apa.org
Bipolar disorder (BD) has been associated with marked cognitive impairment, including
euthymic periods. Attention is among the most compromised functions in BD. Changes …
euthymic periods. Attention is among the most compromised functions in BD. Changes …
Pharmacotherapy of cognition in schizophrenia
HY Meltzer - Current Opinion In Behavioral Sciences, 2015 - Elsevier
Highlights•Atypical antipsychotic drugs (AAPDs) improve some domains of cognition in
schizophrenia (CIS).•The AAPD-induced improvement in CIS exceeds practice effect …
schizophrenia (CIS).•The AAPD-induced improvement in CIS exceeds practice effect …
Effects of psychosis-associated genetic markers on brain volumetry: a systematic review of replicated findings and an independent validation
Background Given psychotic illnesses' high heritability and associations with brain structure,
numerous neuroimaging-genetics findings have been reported in the last two decades …
numerous neuroimaging-genetics findings have been reported in the last two decades …