A practical guide to the oral microbiome and its relation to health and disease

K Krishnan, T Chen, BJ Paster - Oral diseases, 2017 - Wiley Online Library
The oral microbiome is incredibly complex with the average adult harboring about 50–100
billion bacteria in the oral cavity, which represent about 200 predominant bacterial species …

The oral microbiome of children: development, disease, and implications beyond oral health

A Gomez, KE Nelson - Microbial ecology, 2017 - Springer
In the era of applied meta-omics and personalized medicine, the oral microbiome is a
valuable asset. From biomarker discovery to being a powerful source of therapeutic targets …

The role of bacterial biofilms in dental caries and periodontal and peri-implant diseases: a historical perspective

APV Colombo, ACR Tanner - Journal of dental research, 2019 - journals.sagepub.com
Over the last hundred years, groundbreaking research in oral microbiology has provided a
broad and deep understanding about the oral microbiome, its interactions with our body …

Exploring the microbiome of healthy and diseased peri‐implant sites using Illumina sequencing

I Sanz‐Martin, J Doolittle‐Hall, RP Teles… - Journal of clinical …, 2017 - Wiley Online Library
Aim To compare the microbiome of healthy (H) and diseased (P) peri‐implant sites and
determine the core peri‐implant microbiome. Materials and Methods Submucosal biofilms …

Porphyromonas gingivalis is the most abundant species detected in coronary and femoral arteries

JLC Mougeot, CB Stevens, BJ Paster… - Journal of oral …, 2017 - Taylor & Francis
An association between oral bacteria and atherosclerosis has been postulated. A limited
number of studies have used 16S RNA gene sequencing-based metagenomics approaches …

Association between nitrate‐reducing oral bacteria and cardiometabolic outcomes: results from ORIGINS

CE Goh, P Trinh, PC Colombo… - Journal of the …, 2019 - Am Heart Assoc
Background The enterosalivary nitrate‐nitrite‐nitric oxide pathway is an alternative pathway
of nitric oxide generation, potentially linking the oral microbiome to insulin resistance and …

Nitrite generating and depleting capacity of the oral microbiome and cardiometabolic risk: results from ORIGINS

CE Goh, B Bohn, C Marotz, R Molinsky… - Journal of the …, 2022 - Am Heart Assoc
Background The enterosalivary nitrate–nitrite–nitric oxide (NO3–NO2–NO) pathway
generates NO following oral microbiota‐mediated production of salivary nitrite, potentially …

Oral microbiome and cancer therapy-induced oral mucositis

JLC Mougeot, CB Stevens, DS Morton… - JNCI …, 2019 - academic.oup.com
Abstract Characterization of the role of oral microbiome in cancer therapy-induced oral
mucositis (CTOM) is critical in preventing the clinically deleterious effects on patients' health …

Oral microbiomes of patients with infective endocarditis (IE): a comparative pilot study of IE patients, patients at risk for IE and healthy controls

JLC Mougeot, M Beckman, BJ Paster… - Journal of Oral …, 2023 - Taylor & Francis
Background Infective endocarditis (IE) is an uncommon disease with high morbidity and
mortality rates, which often develops from oral bacterial species entering circulation …

Haemophilus pittmaniae and Leptotrichia spp. Constitute a Multi-Marker Signature in a Cohort of Human Papillomavirus-Positive Head and Neck Cancer Patients

JLC Mougeot, MF Beckman, HC Langdon… - Frontiers in …, 2022 - frontiersin.org
Objectives Human papillomavirus (HPV) is a known etiological factor of oropharyngeal head
and neck cancer (HNC). HPV positivity and periodontal disease have been associated with …