Intelligent vascularized 3D/4D/5D/6D-printed tissue scaffolds

X Han, Q Saiding, X Cai, Y Xiao, P Wang, Z Cai… - Nano-Micro Letters, 2023 - Springer
Blood vessels are essential for nutrient and oxygen delivery and waste removal. Scaffold-
repairing materials with functional vascular networks are widely used in bone tissue …

A sugary solution: Harnessing polysaccharide-based materials for osteoporosis treatment

B Zhang, Z Zhou, Y Zhang, Y Miu, C Jin, W Ding… - Carbohydrate …, 2024 - Elsevier
Osteoporosis, a prevalent skeletal disorder characterized by diminished bone density,
compromised microstructure, and heightened fracture susceptibility, poses a growing public …

Alendronate PtIV Prodrug Amphiphile for Enhanced Chemotherapy Targeting and Bone Destruction Inhibition in Osteosarcoma

K Sun, L Yuan, S Chen, Y Sun… - Advanced Healthcare …, 2024 - Wiley Online Library
Chemotherapy remains the primary treatment method for osteosarcoma after surgery.
However, the lack of selectivity of chemotherapy for osteosarcoma leads to unpredictable …

Effects of calcium chloride on the gelling and digestive characteristics of myofibrillar protein in Litopenaeus vannamei

K Zhang, Y Wang, X Fan, N Li, Z Tan, H Liu, X Liu… - Food Chemistry, 2024 - Elsevier
In this study, the effects of CaCl 2 (0, 25, 50, 75, and 100 mM) on the gelling and digestive
properties of the myofibrillar protein (MP) in Litopenaeus vannamei were investigated. The …

Osteoporosis management-current and future perspectives–A systemic review

RJ Anish, A Nair - Journal of Orthopaedics, 2024 - Elsevier
Introduction Osteoporosis is a geriatric metabolic ailment distinguished by low bone mineral
density (BMD) and strength with enhanced micro-architectural retrogression of the …

Metal–Organic Framework‐Integrated Composites for Bone Tissue Regeneration

B Mi, Y Xiong, Y Zhao, Z Lin, L Lu… - Advanced Functional …, 2024 - Wiley Online Library
Metal–organic frameworks (MOFs) exhibit exceptional characteristics, including high
porosity and adjustable properties, rendering them highly suitable for biomedical …

Bone Destruction-Chemotactic Osteoprogenitor Cells Deliver Liposome Nanomedicines for the Treatment of Osteosarcoma and Osteoporosis

Y Chen, QW Chen, FS Fu, HY Gu, A Yu, XZ Zhang - ACS nano, 2024 - ACS Publications
Therapeutic efficacy of skeletal diseases is usually limited by unfavorable drug delivery due
to incapable bone targeting and low bone affinity of conventional drug carriers, as well as …

Osteosarcoma-Targeting PtIV Prodrug Amphiphile for Enhanced Chemo-Immunotherapy via Ca2+ trapping

J Yan, D Wei, Z Zhao, K Sun, Y Sun - Acta Biomaterialia, 2024 - Elsevier
Platinum (Pt II)-based anticancer agents exhibit a lack of selectivity in the treatment of
osteosarcoma, resulting in significant toxicity. Furthermore, immune surveillance withinthe …

Poly (lactide-co-glycolide)-based nanocomposite reinforced by a novel hybrid nanohydroxyapatite

L Jiang, Y Ma, S Tang, Y Zhang, S Su - Journal of Materials Science, 2023 - Springer
To obtain a high-performance poly (lactide-co-glycolide)(PLGA)-based composite, a novel
functionalized hybrid nanohyoxyapatite (n-HA) was proposed by introducing carboxymethyl …

[HTML][HTML] Fluffy hybrid nanoadjuvants for reversing the imbalance of osteoclastic and osteogenic niches in osteoporosis

G Zhang, Y Kang, J Dong, D Shi, Y Xiang, H Gao… - Bioactive Materials, 2024 - Elsevier
Osteoporosis is majorly caused by an imbalance between osteoclastic and osteogenic
niches. Despite the development of nationally recognized first-line anti-osteoporosis drugs …