Long non-coding RNAs (lncRNAs) have emerged as pivotal regulators of gene expression,
contributing significantly to a diverse range of cellular processes, including apoptosis. One …

Aging is the main risk factor for chronic diseases and disablement in human societies with a
great impact in social and health care expenditures. So far, aging and, eventually, death are …

Background Senescent adipose-derived stem cells (ASCs) exhibit reduced therapeutic
efficacy during wound healing. Transcriptional regulation factors including long noncoding …

Regulatory T (Treg) cells modulate several aging-related liver diseases. However, the
molecular mechanisms regulating Treg function in this context are unknown. Here we …

Aging is linked to the deterioration of many physical and cognitive abilities and is the leading
risk factor for Alzheimer's disease. The growing aging population is a significant healthcare …

Epithelial–mesenchymal transition (EMT) is a cellular process by which differentiated
epithelial cells undergo a phenotypic conversion to a mesenchymal nature. The EMT has …

The recently discovered human lncRNA NORAD is induced after DNA damage in a p53-
dependent manner. It plays a critical role in the maintenance of genomic stability through …

HIV-1 infection in the era of combined antiretroviral therapy has been associated with
premature aging. Among the various features of HIV-1 associated neurocognitive disorders …

Abstract Background Long non-coding RNAs (lncRNAs) represent a substantial portion of
the human transcriptome. LncRNAs present a very stringent cell-type/tissue specificity being …

Osteosarcoma is a common and highly malignant bone tumor among children, adolescents
and young adults. However, the underlying molecular mechanisms remain largely …