Emerging non-invasive approaches for diagnosis and monitoring of portal hypertension

X Qi, A Berzigotti, A Cardenas… - … lancet Gastroenterology & …, 2018 - thelancet.com
Clinically significant portal hypertension is associated with an increased risk of developing
gastro-oesophageal varices and hepatic decompensation. Hepatic venous pressure …

Noninvasive diagnostics for portal hypertension: a comprehensive review

M Mandorfer, V Hernández-Gea… - Seminars in liver …, 2020 - thieme-connect.com
Noninvasive diagnostics for portal hypertension include imaging and functional tests, as well
as blood-based biomarkers, and capture different features of the portal hypertensive …

MR elastography‐based liver fibrosis correlates with liver events in nonalcoholic fatty liver patients: a multicenter study

MAT Han, A Vipani, N Noureddin, K Ramirez… - Liver …, 2020 - Wiley Online Library
Abstract Background & Aims Liver fibrosis assessed by liver biopsy is predictive of clinical
liver events in patients with nonalcoholic fatty liver disease (NAFLD). Magnetic resonance …

Mesenchymal stem cell-derived exosomal miR-27b-3p alleviates liver fibrosis via downregulating YAP/LOXL2 pathway

F Cheng, F Yang, Y Wang, J Zhou, H Qian… - Journal of …, 2023 - Springer
Abstract Lysyl oxidase-like 2 (LOXL2) is an extracellular copper-dependent enzyme that
plays a central role in fibrosis by catalyzing the crosslinking and deposition of collagen …

Development and validation of a radiomics signature for clinically significant portal hypertension in cirrhosis (CHESS1701): a prospective multicenter study

F Liu, Z Ning, Y Liu, D Liu, J Tian, H Luo, W An… - …, 2018 - thelancet.com
Clinically significant portal hypertension (CSPH) is associated with an incremental risk of
esophageal varices and overt clinical decompensations. However, hepatic venous pressure …

MR elastography outperforms shear wave elastography for the diagnosis of clinically significant portal hypertension

P Kennedy, D Stocker, G Carbonell, D Said, O Bane… - European …, 2022 - Springer
Objectives Portal hypertension (PH) is associated with complications such as ascites and
esophageal varices and is typically diagnosed through invasive hepatic venous pressure …

Origins of portal hypertension in nonalcoholic fatty liver disease

G Baffy - Digestive diseases and sciences, 2018 - Springer
Nonalcoholic fatty liver disease (NAFLD) advanced to cirrhosis is often complicated by
clinically significant portal hypertension, which is primarily caused by increased intrahepatic …

Primary prevention of bleeding from esophageal varices in patients with liver cirrhosis: An update and review of the literature

DV Garbuzenko, NO Arefyev - Journal of Evidence‐Based …, 2020 - Wiley Online Library
All patients with liver cirrhosis and portal hypertension should be stratified by risk groups to
individualize different therapeutic strategies to increase the effectiveness of treatment. In this …

[HTML][HTML] Nonalcoholic fatty liver disease and portal hypertension

M Ryou, N Stylopoulos, G Baffy - Exploration of medicine, 2020 - ncbi.nlm.nih.gov
Nonalcoholic fatty liver disease (NAFLD) is a substantial and growing problem worldwide
and has become the second most common indication for liver transplantation as it may …

Using MR elastography to assess portal hypertension and response to beta‐blockers in patients with cirrhosis

KV Danielsen, JD Hove, P Nabilou, M Yin… - Liver …, 2021 - Wiley Online Library
Background MR elastography can determine organ‐related stiffness, which reflects the
degree of fibrosis. Liver stiffness increases in cirrhosis, and stiffness increases further post …