A review of current practice in the design and analysis of extremely small stepped-wedge cluster randomized trials

G Tong, P Nevins, M Ryan, K Davis-Plourde… - Clinical …, 2024 - journals.sagepub.com
Background/Aims Stepped-wedge cluster randomized trials tend to require fewer clusters
than standard parallel-arm designs due to the switches between control and intervention …

A systematic review of stepped wedge cluster randomized trials in high impact journals: assessing the design, rationale, and analysis

E Varghese, A Briola, T Kennel, A Pooley… - Journal of Clinical …, 2024 - Elsevier
Objective Stepped wedge cluster randomized trials (SW-CRTs) are an appealing study
design because they enable sequential roll out of an intervention across clusters, bringing …

How to achieve model-robust inference in stepped wedge trials with model-based methods?

B Wang, X Wang, F Li - Biometrics, 2024 - academic.oup.com
ABSTRACT A stepped wedge design is an unidirectional crossover design where clusters
are randomized to distinct treatment sequences. While model-based analysis of stepped …

Maintaining the validity of inference from linear mixed models in stepped-wedge cluster randomized trials under misspecified random-effects structures

Y Ouyang, M Taljaard, AB Forbes… - Statistical Methods in …, 2024 - journals.sagepub.com
Linear mixed<? show [AQ ID= GQ2 POS=-18pt]?><? show [AQ ID= GQ4]?><? show [AQ ID=
GQ5 POS= 12pt]?> models are commonly used in analyzing stepped-wedge cluster …

Model‐assisted analysis of covariance estimators for stepped wedge cluster randomized experiments

X Chen, F Li - Scandinavian Journal of Statistics, 2024 - Wiley Online Library
Stepped wedge cluster randomized experiments (SW‐CREs) represent a class of
unidirectional crossover designs. Although SW‐CREs have become popular, definitions of …

Estimates of intra-cluster correlation coefficients from 2018 USA Medicare data to inform the design of cluster randomized trials in Alzheimer's and related dementias

Y Ouyang, F Li, X Li, J Bynum, V Mor, M Taljaard - Trials, 2024 - Springer
Abstract Background Cluster randomized trials (CRTs) are increasingly important for
evaluating interventions embedded in health care systems. An essential parameter in …

A Generalized Difference-in-Differences Estimator for Unbiased Estimation of Desired Estimands from Staggered Adoption and Stepped-Wedge Settings

L Kennedy-Shaffer - arXiv preprint arXiv:2405.08730, 2024 - arxiv.org
Staggered treatment adoption arises in the evaluation of policy impact and implementation
in a variety of settings. This occurs in both randomized stepped-wedge trials and non …

Analysis of cohort stepped wedge cluster-randomized trials with non-ignorable dropout via joint modeling

A Gasparini, MJ Crowther, EO Hoogendijk, F Li… - arXiv preprint arXiv …, 2024 - arxiv.org
Stepped wedge cluster-randomized trial (CRTs) designs randomize clusters of individuals to
intervention sequences, ensuring that every cluster eventually transitions from a control …

Assessing mediation in cross-sectional stepped wedge cluster randomized trials

Z Cao, F Li - arXiv preprint arXiv:2410.15596, 2024 - arxiv.org
Mediation analysis has been comprehensively studied for independent data but relatively
little work has been done for correlated data, especially for the increasingly adopted stepped …

A sensitivity analysis approach to principal stratification with a continuous longitudinal intermediate outcome: Applications to a cohort stepped wedge trial

L Yang, MJ Daniels, F Li - arXiv preprint arXiv:2412.00926, 2024 - arxiv.org
Causal inference in the presence of intermediate variables is a challenging problem in many
applications. Principal stratification (PS) provides a framework to estimate principal causal …