Modeling development of breast cancer: from tumor microenvironment to preclinical applications

R Tang, XQ Liu - Frontiers in Pharmacology, 2024 - frontiersin.org
Breast cancer is a complex disease and its progression is related not only to tumor cells but
also to its microenvironment, which can not be sufficiently reflected by the traditional …

Artificial intelligence-driven new drug discovery targeting serine/threonine kinase 33 for cancer treatment

NL Tran, H Kim, CH Shin, E Ko, SJ Oh - Cancer Cell International, 2023 - Springer
Background Artificial intelligence (AI) is capable of integrating a large amount of related
information to predict therapeutic relationships such as disease treatment with known drugs …

[HTML][HTML] Macrophage colony-stimulating factor and its role in the tumor microenvironment: novel therapeutic avenues and mechanistic insights

L Yi, Y Gai, Z Chen, K Tian, P Liu, H Liang, X Xu… - Frontiers in …, 2024 - frontiersin.org
The tumor microenvironment is a complex ecosystem where various cellular and molecular
interactions shape the course of cancer progression. Macrophage colony-stimulating factor …

[HTML][HTML] Advancing osteosarcoma 3D modeling in vitro for novel tumor microenvironment-targeted therapies development

S Costa, J Rodrigues, C Vieira, S Dias, J Viegas… - Journal of Controlled …, 2024 - Elsevier
Osteosarcoma (OS) represents one of the most common primary bone cancers affecting
children and young adults. The available treatments have remained unimproved for the past …