[HTML][HTML] The reversibility of cellular mechano-activation

AEM Beedle, P Roca-Cusachs - Current Opinion in Cell Biology, 2023 - Elsevier
The cellular microenvironment is highly heterogeneous and dynamic. Therefore, cells must
be equipped with molecular tools to adapt and respond to constantly fluctuating inputs. One …

The structure and mechanics of the cell cortex depend on the location and adhesion state

DAD Flormann, L Kainka, G Montalvo, C Anton… - Proceedings of the …, 2024 - pnas.org
Cells exist in different phenotypes and can transition between them. A phenotype may be
characterized by many different aspects. Here, we focus on the example of whether the cell …

Appetizer on soft matter physics concepts in mechanobiology

Y Lou - Development, Growth & Differentiation, 2023 - Wiley Online Library
Mechanosensing, the active responses of cells to the mechanics on multiple scales, plays
an indispensable role in regulating cell behaviors and determining the fate of biological …

Contrastive learning through non-equilibrium memory

M Falk, A Strupp, B Scellier, A Murugan - arXiv preprint arXiv:2312.17723, 2023 - arxiv.org
Learning algorithms based on backpropagation have enabled transformative technological
advances but alternatives based on local energy-based rules offer benefits in terms of …

Actin crosslinker competition and sorting drive emergent GUV size-dependent actin network architecture

Y Bashirzadeh, SA Redford, C Lorpaiboon… - Communications …, 2021 - nature.com
The proteins that make up the actin cytoskeleton can self-assemble into a variety of
structures. In vitro experiments and coarse-grained simulations have shown that the actin …

Adaptive nonequilibrium design of actin-based metamaterials: Fundamental and practical limits of control

S Chennakesavalu, SK Manikandan… - Proceedings of the …, 2024 - National Acad Sciences
The adaptive and surprising emergent properties of biological materials self-assembled in
far-from-equilibrium environments serve as an inspiration for efforts to design nanomaterials …

Electromechanical interactions between cell membrane and nuclear envelope: Beyond the standard Schwan's model of biological cells

E Sabri, C Brosseau - Bioelectrochemistry, 2024 - Elsevier
We investigate little-appreciated features of the hierarchical core–shell (CS) models of the
electrical, mechanical, and electromechanical interactions between the cell membrane (CM) …

Microarchitected compliant scaffolds of pyrolytic carbon for 3D muscle cell growth

M Taale, B Schamberger, MA Monclus… - Advanced …, 2024 - Wiley Online Library
The integration of additive manufacturing technologies with the pyrolysis of polymeric
precursors enables the design‐controlled fabrication of architected 3D pyrolytic carbon …

Simulating structured fluids with tensorial viscoelasticity

C Floyd, S Vaikuntanathan, AR Dinner - The Journal of Chemical …, 2023 - pubs.aip.org
We consider an immersed elastic body that is actively driven through a structured fluid by a
motor or an external force. The behavior of such a system generally cannot be solved …

Simulations of dynamically cross-linked actin networks: morphology, rheology, and hydrodynamic interactions

O Maxian, RP Peláez, A Mogilner… - PLoS computational …, 2021 - journals.plos.org
Cross-linked actin networks are the primary component of the cell cytoskeleton and have
been the subject of numerous experimental and modeling studies. While these studies have …