Paraquat (PQ) is a widely characterized neurotoxicant able to induce a series of nervous
system disorders, including neurobehavioral defects and neurodegenerative diseases …

Background Leucine-rich repeat kinase 2 (LRRK2) is a common gene implicated in
Parkinson's disease (PD) and is also thought to be fundamentally involved in numerous …

Abstract Paraquat (PQ), a non-selective contact herbicide, has been generally accepted as
one of the environmental neurotoxicants. Despite the direct evidence that PQ could induce …

There is a growing number of epidemiological and molecular studies which suggest that
diabetes is associated with an increased risk of Parkinson's disease (PD). Hence, in this …

Paraquat (PQ) has been widely acknowledged as an environmental risk factor for
Parkinson's disease (PD). However, the interaction between splicing factor and long non …

Exposure to the herbicides Paraquat and Roundup® may cause cell lesions due to an
increase in oxidative stress levels in different biological systems, even in the liver. The aim of …

This study investigated the effects of the long-term dietary fish oil supplementation or the
acute administration of the omega-3 fatty acid docosahexaenoic acid (DHA) in the mouse …

The rats were randomly divided into paraquat group, curcumin treatment group, and
pirfenidone treatment group. The concentration of paraquat in rat plasma was determined by …

Paraquat (PQ) is associated with multiple nervous system disorders including Parkinson's
disease. Despite the evidence that PQ could induce inflammatory responses in the central …

Assessments of respiratory response and animal activity are useful endpoints in drug
pharmacology and safety research. We investigated whether continuous, direct monitoring …