Interventions for age-related macular degeneration: are practice guidelines based on systematic reviews?

K Lindsley, T Li, E Ssemanda, G Virgili, K Dickersin - Ophthalmology, 2016 - Elsevier
Purpose Are existing systematic reviews of interventions for age-related macular
degeneration incorporated into clinical practice guidelines? Design High-quality systematic …

Treatment as required versus regular monthly treatment in the management of neovascular age-related macular degeneration: a systematic review and meta-analysis

CM Schmucker, G Rücker, H Sommer, G Virgili… - PLoS …, 2015 - journals.plos.org
Background To investigate whether treatment as required 'pro re nata'(PRN) versus regular
monthly treatment regimens lead to differences in outcomes in neovascular age-related …

Recurrence rate of choroidal neovascularization in neovascular age-related macular degeneration managed with a treat–extend–stop protocol

SD Adrean, S Chaili, S Grant, A Pirouz - Ophthalmology Retina, 2018 - Elsevier
Purpose To examine visual outcomes and recurrence rates in patients with choroidal
neovascularization (CNV) resulting from neovascular age-related macular degeneration …

The Finnish national guideline for diagnosis, treatment and follow‐up of patients with wet age‐related macular degeneration

R Tuuminen, H Uusitalo‐Järvinen… - Acta …, 2017 - Wiley Online Library
Age‐related macular degeneration (AMD) is the main cause of visual impairment in
developed countries. Several improvements in the visualization of posterior segment of the …

Effectiveness of bevacizumab step therapy for neovascular age-related macular degeneration

J Siktberg, SJ Kim, P Sternberg Jr, S Patel - Eye, 2023 - nature.com
Objective To determine the effectiveness of bevacizumab step therapy for neovascular age-
related macular degeneration (nAMD) in routine clinical practice. Methods In this …

Cost‐effectiveness of treating wet age‐related macular degeneration at the Kuopio University Hospital in Finland based on a two‐eye Markov transition model

P Vottonen, E Kankaanpää - Acta ophthalmologica, 2016 - Wiley Online Library
Purpose Wet age‐related macular degeneration (AMD) is the leading cause of blindness
worldwide, which can be treated with regular intraocular anti‐vascular endothelial growth …

Appraising the quality of systematic reviews for age-related macular degeneration interventions: a systematic review

LE Downie, E Makrai, Y Bonggotgetsakul… - JAMA …, 2018 - jamanetwork.com
Importance Age-related macular degeneration (AMD) is a leading cause of vision
impairment. It is imperative that AMD care is timely, appropriate, and evidence-based. It is …

Antivascular endothelial growth factor dosing and expected acuity outcome at 1 year

RF Spaide - Retina, 2021 - journals.lww.com
Purpose: To determine the dose–response characteristics of the antivascular endothelial
growth factor agents ranibizumab and aflibercept in neovascular age-related macular …

Recent advances in developing photosensitizers for photodynamic cancer therapy

C Chen, J Wang, X Li, X Liu… - Combinatorial chemistry & …, 2017 - ingentaconnect.com
Background & Aim: Photosensitizers are key molecules used in photodynamic cancer
therapy (PDT), which is an effective therapeutic modality option for several diseases and …

Ranibizumab Modifies the Expression of Metalloproteinases and Their Tissue Inhibitors in Peripheral Blood Mononuclear Cells in Patients with Exudative Age …

B Strzalka-Mrozik, O Paprzycka, O Gruszka… - Journal of Clinical …, 2024 - mdpi.com
Background: Age-related macular degeneration (AMD) is the leading cause of vision loss in
people over 60 years of age. Despite research, the causes of AMD remain unclear. Matrix …