MicroRNAs (miRNAs) are short non-coding RNAs that inhibit the expression of target genes
by directly binding to their mRNAs. miRNAs are transcribed as precursor molecules, which …

MicroRNAs (miRNAs) are approximately 22-nucleotide-long, small non-coding RNAs that
post-transcriptionally regulate gene expression. The biogenesis of miRNAs involves multiple …

The widespread implementation of mass sequencing has revealed a diverse landscape of
small RNAs derived from larger precursors. Whilst many of these are likely to be byproducts …

The proper formation and function of neuronal networks is required for cognition and
behavior. Indeed, pathophysiological states that disrupt neuronal networks can lead to …

Since the establishment of a canonical animal microRNA biogenesis pathway driven by the
RNase III enzymes Drosha and Dicer, an unexpected variety of alternative mechanisms that …

Simple Summary Hepatocellular carcinoma (HCC) is one of the most frequently occurring
cancers, and the prognosis for late-stage HCC remains poor. A better understanding of the …

MicroRNAs are small noncoding RNAs that regulate gene expression at the
posttranscriptional level in a sequence-specific manner. After their discovery in 1993 …

MicroRNAs (miRNAs) are small, noncoding RNAs that mediate posttranscriptional gene
suppression in a sequence-specific manner. The ability of a single miRNA species to target …

Atypical miRNA substrates do not fit criteria often used to annotate canonical miRNAs, and
can escape the notice of miRNA genefinders. Recent analyses expanded the catalogs of …

Over the recent years, Next Generation Sequencing (NGS) technologies targeting the
microRNA transcriptome revealed the existence of many different RNA fragments derived …