[HTML][HTML] 2020 WHO classification of female genital tumors

AK Höhn, CE Brambs, GGR Hiller… - Geburtshilfe und …, 2021 - thieme-connect.com
In der WHO-Klassifikation 2020 steht die Unterscheidung von HPV-assoziierten und HPV-
unabhängigen Plattenepithelkarzinomen des unteren weiblichen Genitales im Vordergrund …

Vulvar carcinoma: Standard of care and perspectives

C Chargari, J Wasserman, A Gabro… - Journal of Clinical …, 2024 - ascopubs.org
PURPOSE Treatment of vulvar carcinoma (VC) is challenging. The objectives of this review
were to describe for clinicians the epidemiologic and clinical aspects of VC, the standard of …

Surgical resection based on ontogenetic cancer field theory for cervical cancer: mature results from a single-centre, prospective, observational, cohort study

M Höckel, B Wolf, K Schmidt, M Mende, B Aktas… - The Lancet …, 2019 - thelancet.com
Background Previous findings from our centre suggest that carcinoma of the cervix
propagates within ontogenetic cancer fields, tissue compartments defined by staged …

Sentinel Lymph node detection in endometrial cancer-Anatomical and scientific facts

R Kimmig, F Thangarajah, P Buderath - Best Practice & Research Clinical …, 2024 - Elsevier
Anatomical and functional aspects of the lymphatic drainage of the uterine corpus in
endometrial cancer are demonstrated. Main lymphatic pathway runs along the upper pelvic …

Molecular subclassification of vulvar squamous cell carcinoma: reproducibility and prognostic significance of a novel surgical technique

EF Thompson, L Hoang, AK Höhn, A Palicelli… - International Journal of …, 2022 - ijgc.bmj.com
Objectives Vulvar squamous cell carcinoma is subclassified into three prognostically
relevant groups:(i) human papillomavirus (HPV) associated,(ii) HPV independent p53 …

The order of cancer: a theory of malignant progression by inverse morphogenesis

M Höckel, U Behn - Frontiers in oncology, 2019 - frontiersin.org
Local spread patterns of malignant tumors follow permissive tissue territories, ie, cancer
fields, as shown for cervical and vulvar carcinoma. The cancer fields are associated in …

Quality of life and associated factors after surgical treatment of vulvar cancer by vulvar field resection (VFR)

S Trott, M Höckel, N Dornhöfer, K Geue, B Aktas… - Archives of Gynecology …, 2020 - Springer
Purpose To investigate patient-reported quality of life (QoL) and associated factors in vulvar
cancer patients treated surgically by vulvar field resection (VFR) without adjuvant radiation …

[HTML][HTML] Total mesometrial resection (TMMR) for cervical cancer FIGO IB–IIA: first results from the multicentric TMMR register study

P Buderath, M Stukan, W Ruhwedel… - Journal of …, 2022 - ncbi.nlm.nih.gov
Available data on total mesometrial resection and therapeutic lymphadenectomy (TMMR+
tLNE) for the treatment of cervical cancer show excellent locoregional control rates without …

TP53 mutation and human papilloma virus status as independent prognostic factors in a Norwegian cohort of vulva squamous cell carcinoma

HN Dongre, R Elnour, S Tornaas… - Acta Obstetricia et …, 2024 - Wiley Online Library
Introduction Vulva squamous cell carcinoma (VSCC) develops through two separate
molecular pathways—one involving high‐risk human papilloma virus infection (HPV …

Epithelial–mesenchymal transition (EMT) in vulvar cancer with and without inguinal lymph node involvement

CE Brambs, LC Horn, M Mende, M Höckel… - Journal of Cancer …, 2022 - Springer
Purpose Epithelial-mesenchymal transition (EMT) is associated with increased metastatic
spread and poor prognosis. Data on vulvar carcinoma are limited. Methods Thirty-two cases …