Lateral entorhinal cortex subpopulations represent experiential epochs surrounding reward
During goal-directed navigation,'what'information, describing the experiences occurring in
periods surrounding a reward, can be combined with spatial 'where'information to guide …
periods surrounding a reward, can be combined with spatial 'where'information to guide …
Different encoding of reward location in dorsal and intermediate hippocampus
Hippocampal place cells fire at specific locations in the environment. They form a cognitive
map that encodes spatial relations in the environment, including reward locations. 1 As part …
map that encodes spatial relations in the environment, including reward locations. 1 As part …
Medial entorhinal cortex mediates learning of context-dependent interval timing behavior
ER Bigus, HW Lee, JC Bowler, J Shi, JG Heys - Nature Neuroscience, 2024 - nature.com
Episodic memory requires encoding the temporal structure of experience and relies on brain
circuits in the medial temporal lobe, including the medial entorhinal cortex (MEC). Recent …
circuits in the medial temporal lobe, including the medial entorhinal cortex (MEC). Recent …
Full field-of-view virtual reality goggles for mice
Visual virtual reality (VR) systems for head-fixed mice offer advantages over real-world
studies for investigating the neural circuitry underlying behavior. However, current VR …
studies for investigating the neural circuitry underlying behavior. However, current VR …
Multiple long-range projections convey position information to the agranular retrosplenial cortex
M Gianatti, AC Garvert, N Lenkey, NC Ebbesen… - Cell reports, 2023 - cell.com
Neuronal signals encoding the animal's position widely modulate neocortical processing.
While these signals are assumed to depend on hippocampal output, their origin has not …
While these signals are assumed to depend on hippocampal output, their origin has not …
Behavior determines the hippocampal spatial mapping of a multisensory environment
Animals behave in multisensory environments guided by various modalities of spatial
information. Mammalian navigation engages a cognitive map of space in the hippocampus …
information. Mammalian navigation engages a cognitive map of space in the hippocampus …
Postsynaptic burst reactivation of hippocampal neurons enables associative plasticity of temporally discontiguous inputs
A fundamental unresolved problem in neuroscience is how the brain associates in memory
events that are separated in time. Here, we propose that reactivation-induced synaptic …
events that are separated in time. Here, we propose that reactivation-induced synaptic …
Hierarchical gradients of encoded spatial and sensory information in the neocortex are attenuated by dorsal hippocampal lesions
AM Demchuk, IM Esteves, HR Chang, J Sun… - Journal of …, 2024 - jneurosci.org
During navigation, the neocortex actively integrates learned spatial context with current
sensory experience to guide behaviors. However, the relative encoding of spatial and …
sensory experience to guide behaviors. However, the relative encoding of spatial and …
Choice of method of place cell classification determines the population of cells identified
Place cells, spatially responsive hippocampal cells, provide the neural substrate supporting
navigation and spatial memory. Historically most studies of these neurons have used …
navigation and spatial memory. Historically most studies of these neurons have used …
NIT: an open-source tool for information theoretic analysis of neural population data
Abstract Information theory provides a popular and principled framework for the analysis of
neural data. It allows to uncover in an assumption-free way how neurons encode and …
neural data. It allows to uncover in an assumption-free way how neurons encode and …