FOXM1 (Forkhead box M1) in tumorigenesis: overexpression in human cancer, implication in tumorigenesis, oncogenic functions, tumor-suppressive properties, and …

I Wierstra - Advances in cancer research, 2013 - Elsevier
Abstract FOXM1 (Forkhead box M1) is a typical proliferation-associated transcription factor
and is also intimately involved in tumorigenesis. FOXM1 stimulates cell proliferation and cell …

Cellular binding partners of the human papillomavirus E6 protein

SS Tungteakkhun, PJ Duerksen-Hughes - Archives of virology, 2008 - Springer
The high-risk strains of human papillomavirus (HR-HPV) are known to be causative agents
of cervical cancer and have recently also been implicated in cancers of the oropharynx. E6 …

Structural and functional analysis of E6 oncoprotein: insights in the molecular pathways of human papillomavirus-mediated pathogenesis

Y Nominé, M Masson, S Charbonnier, K Zanier… - Molecular cell, 2006 - cell.com
Oncoprotein E6 is essential for oncogenesis induced by human papillomaviruses (HPVs).
The solution structure of HPV16-E6 C-terminal domain reveals a zinc binding fold. A model …

Koilocytosis: a cooperative interaction between the human papillomavirus E5 and E6 oncoproteins

E Krawczyk, FA Suprynowicz, X Liu, Y Dai… - The American journal of …, 2008 - Elsevier
A long-recognized, pathognomonic feature of human papillomavirus (HPV) infection is the
appearance of halo or koilocytotic cells in the differentiated layers of the squamous …

Increased expression of HPV-E7 oncoprotein correlates with a reduced level of pRb proteins via high viral load in cervical cancer

BA Mir, A Ahmad, N Farooq, MV Priya, AH Siddiqui… - Scientific Reports, 2023 - nature.com
Human Papillomavirus (HPV) is the most common cause of sexually transmitted diseases
and causes a wide range of pathologies including cervical carcinoma. Integration of the HR …

Molecular mechanism of curcumin induced cytotoxicity in human cervical carcinoma cells

M Singh, N Singh - Molecular and cellular biochemistry, 2009 - Springer
Cervical cancer is the most common cancer in Indian females and is associated with
infection with high risk Human papillomaviruses (HPVs). Curcumin (Diferuloyl methane), a …

Solution structure analysis of the HPV16 E6 oncoprotein reveals a self-association mechanism required for E6-mediated degradation of p53

K Zanier, A ould M'hamed ould Sidi… - Structure, 2012 - cell.com
The viral oncoprotein E6 is an essential factor for cervical cancers induced by" high-risk"
mucosal HPV. Among other oncogenic activities, E6 recruits the ubiquitin ligase E6AP to …

Gene expression analysis of pluri-differentiated mesenchymal progenitor cells and methods for diagnosing a leukemic disease state

B Seshi - US Patent 7,049,072, 2006 - Google Patents
Pluri-differentiated human mesenchymal progenitor cells (MPCs) are isolated. A method
isolates and purifies human mesenchymal progenitor cells from Dexter-type cultures for …

Multistep model of cervical cancer: participation of miRNAs and coding genes

AJG López, JA López - International journal of molecular sciences, 2014 - mdpi.com
Aberrant miRNA expression is well recognized as an important step in the development of
cancer. Close to 70 microRNAs (miRNAs) have been implicated in cervical cancer up to …

Human papillomaviruses and epstein–barr virus interactions in colorectal cancer: A brief review

Q Fernandes, I Gupta, S Vranic, AE Al Moustafa - Pathogens, 2020 - mdpi.com
Human papillomaviruses (HPVs) and the Epstein–Barr virus (EBV) are the most common
oncoviruses, contributing to approximately 10%–15% of all malignancies. Oncoproteins of …