Peptide and protein-based cancer vaccines usually fail to elicit efficient immune responses
against tumors. However, delivery of these peptides and proteins as components within …

In recent years, the practical application of protein-based nanoparticles (PNPs) has
expanded rapidly into areas like drug delivery, vaccine development, and biocatalysis …

Many current cancer vaccine strategies suffer from the inability to mount a CD8 T cell
response that is strong enough to overcome the low immunogenicity of tumors. Viruses …

Currently approved replication-competent and inactivated vaccines are limited by excessive
reactogenicity and poor safety profiles, while subunit vaccines are often insufficiently …

Infectious diseases are a major threat to global human health, yet prophylactic treatment
options can be limited, as safe and efficacious vaccines exist only for a fraction of all …

Purpose The objective of this study is to evaluate the feasibility of using coated
microneedles to deliver vaccines into the oral cavity to induce systemic and mucosal …

Targeted nanoparticles of different origins are considered as new-generation diagnostic and
therapeutic tools. However, there are no targeted drug formulations within the composition of …

We compare immunogenicity and protective efficacy of an HIV vaccine comprised of env and
gag DNA and Env (Envelope) proteins by co-administration of the vaccine components in …

In the recent decades, antibiotic resistance has emerged and spread rapidly among
clinically relevant pathogens. The natural ability of bacteria to transmit resistance …

Abstract Vaccination with HIV/SIV DNAs elicits potent T-cell responses. To improve humoral
immune responses, we combined DNA and protein in a co-immunization protocol using in …