A large body of experimental evidence suggests that neuroinflammation is a key
pathological event triggering and perpetuating the neurodegenerative process associated …

Cancer is the second leading cause of death worldwide. Majority of recent research efforts in
the field aim to address why cancer resistance to therapy develops and how to overcome or …

Parkinson's disease (PD) is one of the most common neurodegenerative movement
disorders which is characterised neuropathologically by progressive loss of dopaminergic …

Over the last 30 years, the 18-kDa TSPO protein has been considered as the PET imaging
biomarker of reference to measure increased neuroinflammation. Generally assumed to …

Several studies have highlighted the roles played by the gut microbiome in central nervous
system diseases. Clinical symptoms and neuropathology have suggested that Parkinson's …

Abstract Gallic acid (3, 4, 5-trihydroxybenzoic acid, GA), a phenolic acid, is ubiquitous in
almost all parts of the plant. In the present study, a neuroinflammatory rat model using …

Behçet's syndrome (BS) is a systemic vasculitis with several clinical manifestations.
Neutrophil hyperactivation mediates vascular BS pathogenesis, via both a massive reactive …

Accumulating evidence suggests that microglia and peripheral immune cells may play
determinant roles in the pathogenesis of Parkinson's disease (PD). Consequently, there is a …

The α-synucleinopathies constitute a subset of neurodegenerative disorders, of which
Parkinson's disease (PD) is the most common worldwide, characterized by the accumulation …

Alzheimer's disease (AD) is a predominantly heterogeneous disease with a highly complex
pathobiology. The presence of amyloid-beta (Aβ) depositions and the accumulation of …