Control of sleep and wakefulness

RE Brown, R Basheer, JT McKenna… - Physiological …, 2012 - journals.physiology.org
This review summarizes the brain mechanisms controlling sleep and wakefulness.
Wakefulness promoting systems cause low-voltage, fast activity in the …

Sleep deprivation and hippocampal vulnerability: changes in neuronal plasticity, neurogenesis and cognitive function

JC Kreutzmann, R Havekes, T Abel, P Meerlo - Neuroscience, 2015 - Elsevier
Despite the ongoing fundamental controversy about the physiological function of sleep,
there is general consensus that sleep benefits neuronal plasticity, which ultimately supports …

The cognitive cost of sleep lost

JG McCoy, RE Strecker - Neurobiology of learning and memory, 2011 - Elsevier
A substantial body of literature supports the intuitive notion that a good night's sleep can
facilitate human cognitive performance the next day. Deficits in attention, learning & memory …

The impact of sleep deprivation on neuronal and glial signaling pathways important for memory and synaptic plasticity

R Havekes, CG Vecsey, T Abel - Cellular signalling, 2012 - Elsevier
Sleep deprivation is a common feature in modern society, and one of the consequences of
sleep loss is the impairment of cognitive function. Although it has been widely accepted that …

The neuroprotective effect of vitamin E on chronic sleep deprivation-induced memory impairment: the role of oxidative stress

KH Alzoubi, OF Khabour, BA Rashid, IM Damaj… - Behavioural Brain …, 2012 - Elsevier
Sleep deprivation induces oxidative stress and impairs learning and memory processes.
Vitamin E, on the other hand, is a strong antioxidant that has neuroprotective effect on the …

Effects of sleep deprivation on neural functioning: an integrative review

TW Boonstra, JF Stins, A Daffertshofer… - Cellular and molecular life …, 2007 - Springer
Sleep deprivation has a broad variety of effects on human performance and neural
functioning that manifest themselves at different levels of description. On a macroscopic …

Hippocampal synaptic plasticity and spatial learning are impaired in a rat model of sleep fragmentation

JL Tartar, CP Ward, JT McKenna… - European Journal of …, 2006 - Wiley Online Library
Sleep fragmentation, a symptom in many clinical disorders, leads to cognitive impairments.
To investigate the mechanisms by which sleep fragmentation results in memory …

Sleep deprivation impairs spatial working memory and reduces hippocampal AMPA receptor phosphorylation

R Hagewoud, R Havekes, A Novati… - Journal of sleep …, 2010 - Wiley Online Library
Sleep is important for brain function and cognitive performance. Sleep deprivation (SD) may
affect subsequent learning capacity and ability to form new memories, particularly in the …

Neurobiological consequences of sleep deprivation

K Alkadhi, M Zagaar, I Alhaider… - Current …, 2013 - ingentaconnect.com
Although the physiological function of sleep is not completely understood, it is well
documented that it contributes significantly to the process of learning and memory. Ample …

Experimental sleep deprivation as a tool to test memory deficits in rodents

V Colavito, PF Fabene, G Grassi-Zucconi… - Frontiers in systems …, 2013 - frontiersin.org
Paradigms of sleep deprivation (SD) and memory testing in rodents (laboratory rats and
mice) are here reviewed. The vast majority of these studies have been aimed at …