In recent decades, the biomedical applications of mesenchymal stem cells (MSCs) have
attracted increasing attention. MSCs are easily extracted from the bone marrow, fat, and …

Human mesenchymal stem cells (MSCs) are currently recognized as a powerful cell source
for regenerative medicine, notably for their capacity to differentiate into multiple cell types …

Human mesenchymal stromal cells (hMSCs) are increasingly used in regenerative medicine
for restoring worn-out or damaged tissue. Newly engineered tissues need to be properly …

Osteoblasts play an important role in the regulation of bone homeostasis throughout life.
Thus, the damage of osteoblasts can lead to serious skeletal diseases, highlighting the …

Bone grafting procedures have become increasingly common in the United States, with
approximately 500,000 cases occurring each year at a societal cost exceeding $2.4 billion …

Actin plays fundamental roles in both the cytoplasm and the cell nucleus. In the nucleus, β‐
actin regulates neuronal reprogramming by consolidating a heterochromatin landscape …

Icariin (ICA) is the main active flavonoid glucoside from herbs of the genus Epimedium; in
traditional Chinese medicine, these herbs have long been prescribed for the treatment of …

Mechanical loading is a potent stimulus of bone adaptation, requiring the replenishment of
the osteoblast from a progenitor population. One such progenitor is the mesenchymal stem …

Abstract Autosomal Dominant Osteopetrosis type II (ADO2) is a rare bone disease of
impaired osteoclastic bone resorption caused by heterozygous missense mutations in the …

Progressive osseous heteroplasia (POH) and fibrous dysplasia (FD) are genetic diseases of
bone formation at opposite ends of the osteogenic spectrum: imperfect osteogenesis of the …