Biomedical research requires both in vitro and in vivo studies in order to explore disease
processes or drug interactions. Foundational investigations have been performed at the …

Biological evaluation of biomedical materials faces constraints imposed by the limitations of
traditional in vitro and animal experiments. Currently, miniaturized and biomimetic …

Polymer composite scaffolds hold promise in bone tissue engineering due to their
biocompatibility, mechanical properties, and reproducibility. Among these materials …

Polydimethylsiloxane (PDMS), commonly used in organ‐on‐a‐chip (OoC) systems, faces
limitations in replicating complex geometries, hindering its effectiveness in creating 3D OoC …

Bone defects are a prevalent issue resulting from various factors, such as trauma,
degenerative diseases, congenital disabilities, and the surgical removal of tumors. Current …

ABSTRACT Bone‐on‐a‐chip (BOC) models that based on microfluidic technology have
widely applied to understand bone physiology and the pathogenesis of related diseases. In …

The replication of bone physiology under laboratory conditions is a prime target behind the
development of in vitro bone models. The model should be robust enough to elicit an …

Abstract Organ-on-a-chip (OOC) facilitates precise manipulation of fluids in microfluidic
chips and simulation of the physiological, chemical, and mechanical characteristics of …

Polydimethylsiloxane (PDMS), commonly used in organ-on-a-chip (OoC) systems, faces
limitations in replicating complex geometries, hindering its effectiveness in creating 3D OoC …

Abstract Three-dimensional (3D) bioprinting is gradually emerging as a popular technique
driving as a new paradigm in tissue engineering. Enhancing cell proliferation and …