Rheological and drug delivery characteristics of poloxamer-based diclofenac sodium formulations for chronic wound site analgesia

J Russo, J Fiegel, NK Brogden - Pharmaceutics, 2020 - mdpi.com
Chronic wounds are a significant and growing health problem, and clinical treatment is often
a painful experience. A topical dosage form would be optimal to treat this pain. Poloxamer …

Behavioral video coding analysis of chronic morphine administration in rats

J Yin, T Zhang, D Li, F Xu, H Li, X Pan… - Biomedical …, 2024 - spandidos-publications.com
The present study assessed the behavior of morphine-addicted rats using behavioral video
coding technology, to evaluate effective methods for identifying morphine addiction. Rats …

Advances in therapeutics and delayed drug release

T Coutant, D Laniesse… - Veterinary Clinics: Exotic …, 2019 - vetexotic.theclinics.com
Medical therapy in exotic pet medicine relies widely on daily or even more frequent oral,
parenteral, or topical drug administration, which can be stressful and even harmful in some …

Evaluation of thermosensitive Poloxamer 407 hydrogels intended to deliver topical analgesic compounds to chronic wound sites

J Russo - 2022 - search.proquest.com
Most wounds heal almost completely within a few weeks of wounding through a well-
regulated process called the “wound cycle,” yet millions of Americans annually suffer from …

Morphine Induces Differential Gene Expression in Transdifferentiated Neuron-Like Cells from Adipose-Derived Stem Cells

S Farrokhfar, T Tiraihi, M Movahedin, H Azizi - Biology Bulletin, 2022 - Springer
Morphine is an opiate drug to alleviate pain; however, it has side effects such as tolerance,
dependence and addiction. In this study, the in vitro effects of morphine on the profile of …