The immune system is a complex, dynamic, and plastic ecosystem composed of multiple cell
types that constantly sense and interact with their local microenvironment to protect from …

In recent years, spatial transcriptomics (ST) technologies have developed rapidly and have
been widely used in constructing spatial tissue atlases and characterizing spatiotemporal …

Changes in gut microbiota have been associated with several diseases. Here, the
International Multiple Sclerosis Microbiome Study (iMSMS) studied the gut microbiome of …

Interpreting the mechanisms and principles that govern gene activity and how these genes
work according to-their cellular distribution in organisms has profound implications for …

Cancer immunotherapy is a method of controlling and eliminating tumors by reactivating the
body's cancer-immunity cycle and restoring its antitumor immune response. The increased …

Interstitial cystitis (IC) is a severely debilitating and chronic disorder with unclear etiology
and pathophysiology, which makes the diagnosis difficult and treatment challenging. To …

The molecular heterogeneity of cancer is one of the major causes of drug resistance that
leads to treatment failure. Thus, better understanding the heterogeneity of cancer will …

Subarachnoid hemorrhage (SAH) is a devastating subtype of stroke with high mortality and
disability rate. Meningeal lymphatic vessels (mLVs) are a newly discovered intracranial fluid …

In vitro tumor models have played vital roles in enhancing the understanding of the cellular
and molecular composition of tumors, as well as their biochemical and biophysical …

Head and neck cancers (HNCs) represent the sixth most widespread malignancy worldwide.
Surgery, radiotherapy, chemotherapeutic and immunotherapeutic drugs represent the main …