Increased cardiovascular risk in rheumatoid arthritis: mechanisms and implications

BR England, GM Thiele, DR Anderson, TR Mikuls - Bmj, 2018 - bmj.com
Rheumatoid arthritis is a systemic autoimmune disease characterized by excess morbidity
and mortality from cardiovascular disease. Mechanisms linking rheumatoid arthritis and …

Disease-modifying anti-rheumatic drugs improve the cardiovascular profile in patients with rheumatoid arthritis

A Giachi, M Cugno, R Gualtierotti - Frontiers in Cardiovascular …, 2022 - frontiersin.org
Rheumatoid arthritis (RA) is a chronic inflammatory disease affecting about 0. 5–1% of the
adult population and manifesting as persistent synovitis, systemic inflammation and …

Weight loss, the obesity paradox, and the risk of death in rheumatoid arthritis

JF Baker, E Billig, K Michaud, S Ibrahim… - Arthritis & …, 2015 - Wiley Online Library
Objective In contrast to what is observed in the general population, a low body mass index
(BMI) has been associated with accelerated mortality in patients with rheumatoid arthritis …

Investigating changes in disease activity as a mediator of cardiovascular risk reduction with methotrexate use in rheumatoid arthritis

TM Johnson, HR Sayles, JF Baker… - Annals of the …, 2021 - ard.bmj.com
Objective Examine the association of methotrexate (MTX) use with cardiovascular disease
(CVD) in rheumatoid arthritis (RA) using marginal structural models (MSM) and determine if …

Associations of hydroxychloroquine use with lipid profiles in rheumatoid arthritis: pharmacologic implications

G Kerr, M Aujero, J Richards, H Sayles… - Arthritis care & …, 2014 - Wiley Online Library
Objective To evaluate the association of hydroxychloroquine (HCQ) use with lipid profiles in
a Veterans Affairs Rheumatoid Arthritis (VARA) cohort. Methods Lipid profiles in HCQ users …

Disease activity, cytokines, chemokines and the risk of incident diabetes in rheumatoid arthritis

JF Baker, BR England, M George, G Cannon… - Annals of the …, 2021 - ard.bmj.com
Purpose Rheumatoid arthritis (RA) is associated with a higher risk of diabetes mellitus (DM).
Our aim was to determine associations between inflammatory disease activity (including …

Changes in body mass related to the initiation of disease‐modifying therapies in rheumatoid arthritis

JF Baker, BC Sauer, GW Cannon… - Arthritis & …, 2016 - Wiley Online Library
Objective Unintentional weight loss is important and can be predictive of long‐term
outcomes in patients with rheumatoid arthritis (RA). This study was undertaken to assess …

Obesity, weight loss, and progression of disability in rheumatoid arthritis

JF Baker, BR England, TR Mikuls… - Arthritis care & …, 2018 - Wiley Online Library
Objective Cross‐sectional studies have demonstrated that obese patients with rheumatoid
arthritis (RA) often report greater disability. The longitudinal effects of obesity, however, are …

Elevations in adipocytokines and mortality in rheumatoid arthritis

JF Baker, BR England, MD George, K Wysham… - …, 2022 - academic.oup.com
Objectives This study assessed whether circulating levels of adiponectin and leptin are
associated with higher mortality in patients with RA. Methods Participants were adults from …

Initiation of disease-modifying therapies in rheumatoid arthritis is associated with changes in blood pressure

JF Baker, B Sauer, CC Teng, M George… - JCR: Journal of …, 2018 - journals.lww.com
Purpose This study reports the effect of disease-modifying therapies for rheumatoid arthritis
(RA) on systolic and diastolic blood pressure (SBP, DBP) over 6 months and incident …