AIM The “2023 ACC/AHA/ACCP/HRS Guideline for the Diagnosis and Management of Atrial
Fibrillation” provides recommendations to guide clinicians in the treatment of patients with …

Ophthalmic epidemiology is concerned with the prevalence, distribution and other factors
relating to human eye disease. While observational studies cannot avoid confounding …

Chronic kidney disease (CKD) is highly prevalent in the elderly population. However, it is
rarely investigated whether kidney function is causally linked to biological aging itself. In this …

Background Ageing traits and frailty are important health issues in modern medicine.
Evidence supporting the causal effects of tobacco smoking on various ageing traits is …

A growing body of research suggests that social or physical activity can affect the risk of
Major depressive disorder (MDD). However, the bidirectional relationship between them …

Background The knowledge gap regarding whether the correlation between atrial fibrillation
(AF) and dementia in observational studies is causation or driven by other shared risk …

Aims/hypothesis: 20–80% of Nonalcoholic Fatty Liver Disease (NAFLD) have been
observed to have dyslipidemia. Nevertheless, the probable mechanism of dyslipidemia's …

Background Previous studies have reported cross-sectional associations between
measures of epigenetic age acceleration (EAA) and kidney function phenotypes. However …

Background The incidences of atrial fibrillation (AF) and chronic kidney disease (CKD) are
increasing, and AF is prevalent in patients with CKD. However, few studies have …

We performed univariable and multivariable Mendelian randomization (MR) analysis to
evaluate the association between blood lipids and risk of atrial fibrillation (AF), including low …