Effect of the SARS-CoV-2 Delta-associated G15U mutation on the s2m element dimerization and its interactions with miR-1307-3p

CL Cunningham, CJ Frye, JA Makowski, AH Kensinger… - RNA, 2023 - rnajournal.cshlp.org
The s2m, a highly conserved 41-nt hairpin structure in the SARS-CoV-2 genome, serves as
an attractive therapeutic target that may have important roles in the virus life cycle or …

NMR characterization and ligand binding site of the stem–loop 2 motif from the Delta variant of SARS-CoV-2

T Matzel, MW Martin, A Herr, A Wacker, C Richter… - RNA, 2024 - rnajournal.cshlp.org
The stem–loop 2 motif (s2m) in SARS-CoV-2 (SCoV-2) is located in the 3′-UTR. Although
s2m has been reported to display characteristics of a mobile genomic element that might …

Interactions of the SARS-CoV-2 Viral Genome 3'-Untranslated Region with Viral and Host RNAs

CJ Frye - 2024 - search.proquest.com
This dissertation focuses on the characterization of RNA-RNA interactions within the severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) genome and with host microRNAs …