Abstract Active Pharmaceutical Ingredients (APIs) do not always exhibit processable
physical properties, which makes their processing in an industrial setup very demanding …

Optimized physical properties (eg, bulk, surface/interfacial, and mechanical properties) of
active pharmaceutical ingredients (APIs) are key to the successful integration of drug …

The cooling crystallization-spherical agglomeration (CCSA) technology proposed in this
work overcomes the disadvantages of complex process and biohazardous solvents, which …

Combining celecoxib with other chemopreventive drugs is a promising method of
chemoprevention for cancer, especially for colorectal cancer. However, the traditional drug …

Vanillin is a natural flavor and is widely used in the fields of medicine, food and
optoelectronics. However, the stable form I of vanillin usually shows needle or fiber-like …

Spherical agglomeration technology can produce high‐performance spherical particles in a
single crystallization unit, although it is still challenging to control the particle size and …

A strategy for rationally selecting solvent systems of spherical agglomeration is proposed for
the first time. It emphasizes that followed by crystallization and phase separation, spherical …

In this study, we investigated the morphology modification of m-aminobenzoic acid (m-ABA)
needle-like crystals using a spherulitic growth strategy to enhance their particle …

In industrial crystallization, spherical crystals have gained increasing interest due to their
excellent physicochemical properties, such as high bulk density, flowability, stability, etc …

Spherical agglomeration is a well-known process intensification method that offers several
advantages, including material and energy savings associated with the reduction of …