Sentrin/small ubiquitin-like modifier (SUMO) is protein modification pathway that regulates
multiple biological processes, including cell division, DNA replication/repair, signal …

Cytokine storm generates during various systemic acute infections, including sepsis and
current pandemic called COVID-19 (severe) causing devastating inflammatory conditions …

Sumoylation is an essential post‐translational modification intimately involved in a diverse
range of eukaryotic cellular mechanisms. Small ubiquitin‐like modifier (SUMO) protein …

Emerging clinical evidence shows that the deregulation of ubiquitin-mediated degradation of
oncogene products or tumour suppressors is likely to be involved in the aetiology of …

A decade has passed since SUMO (small ubiquitin-related modifier) was discovered to be a
reversible post-translational protein modifier. During this time many enzymes that participate …

▪ Abstract Small ubiquitin-related modifier (SUMO) family proteins function by becoming
covalently attached to other proteins as post-translational modifications. SUMO modifies …

The post-translational modification SUMOylation is a major regulator of protein function that
plays an important role in a wide range of cellular processes. SUMOylation involves the …

PML nuclear bodies are matrix-associated domains that recruit an astonishing variety of
seemingly unrelated proteins. Since their discovery in the early 1960s, PML bodies have …

Attachment of ubiquitin to proteins is a crucial step in many cellular regulatory mechanisms
and contributes to numerous biological processes, including embryonic development, the …

Ran is a nuclear Ras-like GTPase that is required for the bidirectional transport of proteins
and ribnucleoproteins across the nuclear pore complex (NPC). A key regulator of the Ran …