Opening the black box: why do euploid blastocysts fail to implant? A systematic review and meta-analysis

D Cimadomo, L Rienzi, A Conforti… - Human …, 2023 - academic.oup.com
BACKGROUND A normal chromosomal constitution defined through PGT-A assessing all
chromosomes on trophectoderm (TE) biopsies represents the strongest predictor of embryo …

Physiological and molecular determinants of embryo implantation

S Zhang, H Lin, S Kong, S Wang, H Wang… - Molecular aspects of …, 2013 - Elsevier
Embryo implantation involves the intimate interaction between an implantation-competent
blastocyst and a receptive uterus, which occurs in a limited time period known as the …

The effects of chemical and physical factors on mammalian embryo culture and their importance for the practice of assisted human reproduction

PL Wale, DK Gardner - Human reproduction update, 2016 - academic.oup.com
BACKGROUND Although laboratory procedures, along with culture media formulations,
have improved over the past two decades, the issue remains that human IVF is performed in …

[HTML][HTML] Maternal diet-induced obesity alters mitochondrial activity and redox status in mouse oocytes and zygotes

N Igosheva, AY Abramov, L Poston, JJ Eckert… - PloS one, 2010 - journals.plos.org
The negative impact of obesity on reproductive success is well documented but the stages at
which development of the conceptus is compromised and the mechanisms responsible for …

Beta-oxidation is essential for mouse oocyte developmental competence and early embryo development

KR Dunning, K Cashman, DL Russell… - Biology of …, 2010 - academic.oup.com
Oocyte and embryo metabolism are closely linked with their subsequent developmental
capacity. Lipids are a potent source of cellular energy, yet little is known about lipid …

[PDF][PDF] Metabolism of the preimplantation embryo: 40 years on

HJ Leese - Reproduction, 2012 - scholar.archive.org
This review considers how our understanding of preimplantation embryo metabolism has
progressed since the pioneering work on this topic in the late 1960s and early 1970s …

Role of fatty acids in energy provision during oocyte maturation and early embryo development

RG Sturmey, A Reis, HJ Leese… - … in Domestic Animals, 2009 - Wiley Online Library
Contents While much is known about the metabolism of exogenous nutrients such as
glucose, lactate, pyruvate, amino acids by oocytes and pre‐implantation mammalian …

[HTML][HTML] Natural selection of human embryos: decidualizing endometrial stromal cells serve as sensors of embryo quality upon implantation

G Teklenburg, M Salker, M Molokhia, S Lavery, G Trew… - PloS one, 2010 - journals.plos.org
Background Pregnancy is widely viewed as dependent upon an intimate dialogue, mediated
by locally secreted factors between a developmentally competent embryo and a receptive …

[HTML][HTML] Extracellular Vesicles from BOEC in In Vitro Embryo Development and Quality

R Lopera-Vasquez, M Hamdi, B Fernandez-Fuertes… - PloS one, 2016 - journals.plos.org
To evaluate the effect of conditioned media (CM) and Extracellular Vesicles (EVs) derived
from bovine oviduct epithelial cell (BOEC) lines on the developmental capacity of bovine …

Diagnosis of human preimplantation embryo viability

DK Gardner, M Meseguer, C Rubio… - Human reproduction …, 2015 - academic.oup.com
BACKGROUND Transfer of more than a single embryo in an IVF cycle comes with the finite
possibility of a multiple gestation. Even a twin pregnancy confers significant risk to both …