Structural characterization of TRAF6 N-terminal for therapeutic uses and computational studies on new derivatives
Tumor necrosis factor receptor-associated factors (TRAFs) are a protein family with a wide
variety of roles and binding partners. Among them, TRAF6, a ubiquitin ligase, possesses …
variety of roles and binding partners. Among them, TRAF6, a ubiquitin ligase, possesses …
Single pulse data collection with an X-ray chopper at in situ room temperature Laue crystallography beamline BL03HB
Abstract in situ room temperature Laue crystallography has gained increasing attention. This
method is suitable for time-resolved Laue crystallography experiments to get crystal …
method is suitable for time-resolved Laue crystallography experiments to get crystal …
[PDF][PDF] Structural analysis of wild-type and Val120Thr mutant Candida boidinii formate dehydrogenase by X-ray crystallography
Candida boidinii NAD+-dependent formate dehydrogenase (CbFDH) has gained significant
attention for its potential application in the production of biofuels and various industrial …
attention for its potential application in the production of biofuels and various industrial …
X-ray Crystallographic and Hydrogen Deuterium Exchange Studies Confirm Alternate Kinetic Models for Homolog Insulin Monomers
Despite the crucial role of various insulin analogs in achieving satisfactory glycemic control,
a comprehensive understanding of their in-solution dynamic mechanisms still holds the …
a comprehensive understanding of their in-solution dynamic mechanisms still holds the …
Experimental and Computational Insights into the Structural Dynamics of the Fc Fragment of IgG1 Subtype from Biosimilar VEGF-Trap
E Destan, E Turkut, A Aldeniz, J Kang, T Tosha… - bioRxiv, 2024 - biorxiv.org
The constant fragment (Fc) of the Immunoglobulin G1 (IgG1) subtype is increasingly
recognized as a crucial scaffold in the development of advanced therapeutics due to its …
recognized as a crucial scaffold in the development of advanced therapeutics due to its …
Insights into Therapeutic Discovery Through the Kelch Domain Structure of Keap1 at Ambient Temperature
The Kelch-like-ECH associated protein 1 (Keap1) is a part of the E3-ubiquitin ligase
complex that binds to Nuclear factor erythroid 2-related factor 2 (Nrf2) protein and facilitates …
complex that binds to Nuclear factor erythroid 2-related factor 2 (Nrf2) protein and facilitates …
The structural studies of Escherichia coli CyaY at ambient and cryogenic temperatures
Frataxin is a 23 KDa mitochondrial iron-binding protein that is involved in biogenesis of iron-
sulfur clusters. A deficiency in frataxin can lead to Friedreich's ataxia, a progressive …
sulfur clusters. A deficiency in frataxin can lead to Friedreich's ataxia, a progressive …
Structural and Dynamic Characterization of Candida boidinii Formate Dehydrogenase by High-Resolution X-ray Crystallography
Candida boidinii NAD+-dependent formate dehydrogenase (Cb FDH) has gained significant
attention for its potential applications in the production of biofuels and various industrial …
attention for its potential applications in the production of biofuels and various industrial …