In the last decades, the communication between the Endoplasmic reticulum (ER) and
mitochondria has obtained great attention: mitochondria-associated membranes (MAMs) …

The endoplasmic reticulum (ER) is the largest organelle of the cell and participates in
multiple essential functions, including the production of secretory proteins, lipid synthesis …

Endoplasmic reticulum (ER) homeostasis requires molecular regulators that tailor
mitochondrial bioenergetics to the needs of protein folding. For instance, calnexin maintains …

The Mitofusin 2 protein (MFN2), encoded by the MFN2 gene, was first described for its role
in mediating mitochondrial fusion. However, MFN2 is now recognized to play additional …

Membrane contact sites between organelles are essential for maintaining cellular
homeostasis, which requires the continuous exchange of signaling molecules, ions …

Mitochondria are of great relevance to health, and their dysregulation is associated with
major chronic diseases. Research on mitochondria—156 brand new publications from 2019 …

Some aquaporins (AQPs) can transport H 2 O 2 across membranes, allowing redox signals
to proceed in and between cells. Unlike other peroxiporins, human AQP11 is an …

Palmitoylation, a lipid-based posttranslational protein modification, plays a crucial role in
regulating various aspects of neuronal function through altering protein membrane …

Calnexin is a type I integral endoplasmic reticulum (ER) membrane protein with an N-
terminal domain that resides in the lumen of the ER and a C-terminal domain that extends …

Objectives Cardiorenal syndrome type-3 (CRS-3) is an abrupt worsening of cardiac function
secondary to acute kidney injury. Mitochondrial dysfunction is a key pathological mechanism …