The existence of a local renin-an-giotensin system (RAS) specific to the hematopoietic bone marrow (BM) microenvironment had been proposed two decades ago. Most of the RAS …
VJ Jokubaitis, L Sinka, R Driessen… - Blood, The Journal …, 2008 - ashpublications.org
Previous studies revealed that mAb BB9 reacts with a subset of CD34+ human BM cells with hematopoietic stem cell (HSC) characteristics. Here we map BB9 expression throughout …
GP Sharma, BL Fish, AC Frei, J Narayanan… - International Journal of …, 2022 - Elsevier
Purpose Radiation-induced lung injury is a major dose-limiting toxicity for thoracic radiation therapy patients. In experimental models, treatment with angiotensin converting enzyme …
SS Narayan, K Lorenz, J Ukkat, C Hoang-Vu… - Thyroid, 2020 - researchgate.net
Running title: ACEs in thyroid cancer Angiotensin converting enzymes ACE and ACE2 in thyroid cancer progression. SS NARAYAN1, Page 1 1 NEOPLASMA accepted, non-corrected …
S Turk, C Turk, MW Akbar, B Kucukkaraduman… - PLoS …, 2020 - journals.plos.org
Despite the availability of various treatment protocols, response to therapy in patients with Acute Myeloid Leukemia (AML) remains largely unpredictable. Transcriptomic profiling …
C Lin, V Datta, D Okwan-Duodu, X Chen… - The FASEB …, 2011 - ncbi.nlm.nih.gov
Inhibition of angiotensin-converting enzyme (ACE) induces anemia in humans and mice, but it is unclear whether ACE is involved in other aspects of hematopoiesis. Here, we …
AF Rodrigues, M Bader - Biochemical Pharmacology, 2023 - Elsevier
The renin-angiotensin system (RAS) comprises a broad set of functional peptides and receptors that play a role in cardiovascular homeostasis and contribute to cardiovascular …
The locally active ligand peptides, mediators, receptors and signalling pathways of the haematopoietic BM (bone marrow) autocrine/paracrine RAS (renin–angiotensin system) …
The local haematopoietic bone marrow (BM) renin—angiotensin system (RAS) mediates pathobiological alterations of haematopoiesis in an autocrine/paracrine/intracrine fashion …