Exposure to stress during critical periods in development can have severe long-term
consequences, increasing overall risk on psychopathology. One of the key stress response …

Major depressive disorder (MDD) will affect one out of every five people in their lifetime and
is the leading cause of disability worldwide. Nevertheless, mechanisms associated with the …

Current diagnosis of depression is based solely on behavioral symptomatology. The
available US Food and Drug Administration–approved treatments for depression have come …

Mounting evidence suggests that acute and chronic stress, especially the stress-induced
release of glucocorticoids, induces changes in glutamate neurotransmission in the prefrontal …

Half a century after the first formulation of the monoamine hypothesis, compelling evidence
implies that long-term changes in an array of brain areas and circuits mediating complex …

Environmental challenges are part of daily life for any individual. In fact, stress appears to be
increasingly present in our modern, and demanding, industrialized society. Virtually every …

Astrocytes are no longer seen as a homogenous population of cells. In fact, recent studies
indicate that astrocytes are morphologically and functionally diverse and play critical roles in …

The present paper reviews astrocyte pathology in major depressive disorder (MDD) and
proposes that reductions in astrocytes and related markers are key features in the pathology …

An update to the classic text that links neuroscience and human behavior in the context of
therapy. This groundbreaking book explores the recent revolution in psychotherapy that has …

Early life stress (ES) increases vulnerability to psychopathology and impairs cognition in
adulthood. These ES‐induced deficits are associated with lasting changes in hippocampal …