The evaluation of potency plays a key role in defining the quality of cellular therapy products
(CTPs). Potency can be defined as a quantitative measure of relevant biologic function …

Regulatory T cells (Tregs) are critical mediators of immune homeostasis and hold significant
promise in the quest for transplantation tolerance. Progress has now reached a critical …

Hastening posttransplantation immune reconstitution is a key challenge in human leukocyte
antigen (HLA)–haploidentical hematopoietic stem-cell transplantation (HSCT). In …

Background aims Mouse models indicate that adoptive transfer of regulatory T cells (Treg)
may suppress graft-versus-host-disease (GvHD) while preserving graft-versus-leukemia …

Regulatory T cells (Tregs) are essential in maintaining peripheral immunological tolerance
by modulating several subsets of the immune system including monocytes. Under …

Regulatory T cells (Treg cells) represent a CD4+ T‐cell lineage that plays a critical role in
restraining immune responses to self and foreign antigens and associated inflammation …

FoxP3+ regulatory T (Treg) cells maintain immune homeostasis, promote self-tolerance, and
have an emerging role in resolving acute inflammation, providing tissue protection, and …

Abstract Foxp3+ T regulatory (Treg) cells suppress inflammation and are essential for
maintaining tissue homeostasis. A growing appreciation of tissue‐specific Treg functions …

Allograft tolerance is the ultimate goal in the field of transplantation immunology. Immature
dendritic cells (imDCs) play an important role in establishing tolerance but have limitations …

Today human leukocyte antigen-haploidentical transplantation is a feasible option for
patients with high-risk acute leukemia who do not have matched donors. Whether it is T-cell …