2H-Azirines in medicinal chemistry

PА Sakharov, MS Novikov, NV Rostovskii - Chemistry of Heterocyclic …, 2021 - Springer
The review presents an analysis of studies published in the period 1971–2020 devoted to
examination of the biological activity of natural and synthetic 2 H-azirine derivatives, their …

Synthesis of various functionalized 2H‐azirines: An updated library

A De, A Majee - Journal of Heterocyclic Chemistry, 2022 - Wiley Online Library
In the current extensive review, we pay special attention to the progress in the synthesis of 2
H‐azirine. Content is organized by several main approaches for the synthesis of 2 H …

Synthesis of 2-(2-Pyridyl)-2H-azirines via Metal-Free C–C Cross-Coupling of Bromoazirines with 2-Stannylpyridines

AV Agafonova, IA Smetanin, NV Rostovskii… - Organic …, 2021 - ACS Publications
A high-yield method for the introduction of a 2-pyridyl substituent in the C2 position of the
three-membered ring of 2-bromo-2 H-azirine-2-carboxylic acid derivatives by the direct cross …

Selective Synthesis of 3-(1H-Tetrazol-5-yl)-indoles from 2H-Azirines and Arynes

C Grosso, C Alves, TJ Sase, NG Alves, AL Cardoso… - ACS …, 2024 - ACS Publications
A new selective synthetic approach to indole derivatives bearing a tetrazole moiety has
been developed. Arynes, generated in situ from o-(trimethylsilyl) aryl triflates and KF, reacted …

Organocatalysts for the Asymmetric Neber reaction: Synthesis of Chiral 2‐(Tetrazol‐5‐yl)‐2H‐Azirines

C Alves, TJ Sase, C Gadelho, D Murtinho… - …, 2023 - Wiley Online Library
Several novel organocatalysts derived from β‐and γ‐lactam‐fused thiazolidines and L‐
phenylalanine‐based thiazolidines were efficiently synthetized. These organocatalysts, as …

Novel 1,2,3-triazole epicinchonas: Transitioning from organocatalysis to biological activities

P Barrulas, EP Carreiro, LF Veiros… - Synthetic …, 2021 - Taylor & Francis
A small family of novel modular monofunctional epi cinchonidine-1, 2, 3-triazole compounds
was prepared in very good overall yield (3 steps from cinchonidine, 49–87% yield) using …

Five-membered ring systems: with more than one N atom

L Yet - Progress in Heterocyclic Chemistry, 2021 - Elsevier
Five-membered ring systems: with more than one N atom - ScienceDirect Skip to main
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Three-membered ring systems

JS Russel - Progress in Heterocyclic Chemistry, 2021 - Elsevier
This chapter is a survey of the synthesis and reactions of three-membered heterocycles
reported during 2019. Primary emphasis has been devoted to the chemistry of epoxides …

Synthesis and HPLC-ECD Study of Cytostatic Condensed O,N-Heterocycles Obtained from 3-Aminoflavanones

Á Szappanos, A Mándi, K Gulácsi, E Lisztes, BI Tóth… - Biomolecules, 2020 - mdpi.com
Racemic chiral O, N-heterocycles containing 2-arylchroman or 2-aryl-2 H-chromene subunit
condensed with morpholine, thiazole, or pyrrole moieties at the C-3-C-4 bond were …

[HTML][HTML] Механистические и синтетические аспекты нуклеофильного замещения при азириновом цикле

АВ Агафонова - 2023 - dissercat.com
Диссертация на тему «Механистические и синтетические аспекты нуклеофильного
замещения при азириновом цикле», скачать бесплатно автореферат по …