Natural products towards the discovery of potential future antithrombotic drugs

MA Islam, F Alam, I Khalil… - Current …, 2016 - ingentaconnect.com
Globally, thrombosis-associated disorders are one of the main contributors to fatalities.
Besides genetic influences, there are some acquired and environmental risk factors …

Strategies for late-stage optimization: Profiling thermodynamics by preorganization and salt bridge shielding

A Sandner, T Hüfner-Wulsdorf, A Heine… - Journal of Medicinal …, 2019 - ACS Publications
Structural fixation of a ligand in its bioactive conformation may, due to entropic reasons,
improve affinity. We present a congeneric series of thrombin ligands with a variety of …

[HTML][HTML] Assessment of clot-lysing and membrane-stabilizing capacity of ascorbic acid: In vitro approach with molecular docking

SN Yadav, MS Al Hasan, B Das, M Shadin, IH Rakib… - Toxicology Reports, 2024 - Elsevier
This study aimed to evaluate the clot-lysing and membrane stabilizing capacities of ascorbic
acid (AA) using in vitro and in silico methods. For this, we used in vitro clot lysis and …

Assessment of clot-lysing and membrane-stabilizing activity of gallic acid through cyclooxygenase-1 and plasminogen interaction pathways

SRK Sah, MS Al Hasan, LK Thakur, M Shadin… - Food Bioscience, 2025 - Elsevier
Gallic acid (GA) is evident to inhibit the platelet activation process, which plays an important
role in preventing and activating blood clots and clot lysis. Moreover, GA has antioxidant …

Investigation of adverse effects of interactions between herbal drugs and natural blood clotting mechanism

MS Adhyapak, MS Kachole - Journal of thrombosis and thrombolysis, 2016 - Springer
Throughout the world, herbal medicines are consumed by most of the patients without
considering their adverse effects. Many herbal medicines/plant extracts have been reported …

[PDF][PDF] Food Bioscience

SRK Sah, MS Al Hasan, LK Thakur, M Shadin… - researchgate.net
Gallic acid (GA) is evident to inhibit the platelet activation process, which plays an important
role in preventing and activating blood clots and clot lysis. Moreover, GA has antioxidant …

[图书][B] YASHTIMADHU (GLYCYRRHIZA GLABRA LINN.) A POTENT MEDICINAL HERB

VS Prajapati - books.google.com
Plants have been major source of medicine in all cultures from ancient times. In the
traditional system, various indigenous plants are being used in the diagnosis, prevention …

Evaluation of adaptogenic activity of Glycyrrhiza glabra L. roots

PM Prabhuram - 2011 - search.proquest.com
Abstract Background and Objective: Stress is one of the leading causes of anxiety and
depression disease, endocrine disease, gastrointestinal and metabolic disorder due to …