Förster resonance energy transfer (FRET) using fluorescent base analogues is a powerful
means of obtaining high-resolution nucleic acid structure and dynamics information that …

The synthesis of 12 analogues of adenine substituted at C-8 by an ω-hydroxyalkyl, ω-
hydroxyalk-1-enyl, or ω-hydroxyalk-1-ynyl chain of various length has been carried out in …

In search of compounds that ameliorate the toxicity of amyloid-β (Aβ) peptides, new
derivatives of tricyclic pyrones (1–7) were synthesized and their biological activities …

Squalenoyl conjugates of semaxanib and sunitinib, two potent antiangiogenic (pyrrolyl)
methylidenyl‐substituted oxindole multitarget tyrosine kinase inhibitors, were synthesized …

Two radiolabeled analogues of 6-benzyloxy-9 H-purin-2-ylamine (O 6-benzylguanine; BG)
potentially useful in the in vivo mapping of O 6-alkylguanine-DNA alkyltransferase (AGT) …

6-Substituted purin-2-ones have been prepared by completely regioselective addition of
Grignard reagents to an N-protected purin-2-one followed by rearomatisation and …

O-tert-Butyldimethylsilylimidazolyl aminals are N, O-acetals that form readily from aldehydes,
and although they function as aldehyde stabilizing and protecting groups under various …

This paper describes the preparation of 9N-[(1′ R, 3′ R)-trans-3′-hydroxycyclopentanyl]
adenine (1), 3N-[(1′ R, 3′ R)-trans-3′-hydoxycyclopentanyl] adenine (2) and 7N-[(1′ R …

This thesis focuses on the design, synthesis and utilization of fluorescent nucleobase
analogues (FBAs). FBAs are an important class of compounds, used in the research of …

This thesis focuses on the design, synthesis and utilization of fluorescent nucleobase
analogues (FBAs). FBAs are an important class of compounds, used in the research of …